diethyl prop-2-yn-1-ylphosphonate

Base Information

• Chemical Name: diethyl prop-2-yn-1-ylphosphonate
• CAS No.: 3201-73-8
• Molecular Formula: C7H13 O3 P
• Molecular Weight: 176.1501
• Mol file: 3201-73-8.mol

Synonyms:Phosphonicacid, 2-propynyl-, diethyl ester (6CI,7CI,8CI,9CI); Diethyl(propargyl)phosphonate; Diethyl prop-2-ynylphosphonate; NSC 222679

Chemical Property of diethyl prop-2-yn-1-ylphosphonate

Chemical Property:

• Vapor Pressure: 0.121mmHg at 25°C
• Boiling Point: 226.8°Cat760mmHg
• Flash Point: 105.1°C
• Density: 1.069g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of diethyl prop-2-yn-1-ylphosphonate

There total 2 articles about diethyl prop-2-yn-1-ylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

propargyl bromide (106-96-7) + triethyl phosphite (122-52-1) → diethyl prop-2-ynylphosphate (3201-73-8)

Guidance literature:

DOI:10.1021/ja01567a067

Reference yield:

→ diethyl prop-2-ynylphosphate (3201-73-8)

Guidance literature:

Propargylbromid, Diethylphosphit, Na, Tetrahydrofuran; neben Propin-(1)-phosphonsaeure-diethylester;

DOI:10.1021/jo01067a057

Reference yield: 78.0%

diethyl prop-2-ynylphosphate (3201-73-8) + 2,3,5-tri-O-benzoyl-β-D-ribofuranosyl azide (7408-41-5) → C33H34N3O10P (1391731-28-4)

Guidance literature:

With copper(II) oxide; In 1,4-dioxane; water; at 90 ℃; for 2h; regioselective reaction;

DOI:10.1016/j.catcom.2012.05.016

upstream raw materials:

propargyl bromide

triethyl phosphite

Downstream raw materials:

5-(1-Diethylphosphono-2-phenylethyl)-3-methylisoxazole

C₁₄H₂₀N₃O₃P

C₃₃H₃₄N₃O₁₀P