Acetone dimethylhydrazone

Base Information

• Chemical Name: Acetone dimethylhydrazone
• CAS No.: 13483-31-3
• Molecular Formula: C5H12N2
• Molecular Weight: 100.164
• Hs Code.: 2928000090
• European Community (EC) Number: 672-743-4
• DSSTox Substance ID: DTXSID40158998
• Nikkaji Number: J47.768K
• Mol file: 13483-31-3.mol

Synonyms:Acetone dimethylhydrazone;13483-31-3;2-Propanone, dimethylhydrazone;ACETONEDIMETHYLHYDRAZONE;N-methyl-N-(propan-2-ylideneamino)methanamine;1,1-dimethyl-2-(propan-2-ylidene)hydrazine;Acetone dimethyl hydrazone;acetone N,N-dimethylhydrazone;SCHEMBL437325;DIMETHYLHYDRAZONE ACETONE;DTXSID40158998;MFCD00059022;BS-23464;A1116;CS-0205033;FT-0691844;Butanoic acid,3,4-diamino-4-oxo-, (3S)-,;D88379;InChI=1/C5H12N2/c1-5(2)6-7(3)4/h1-4H

Chemical Property of Acetone dimethylhydrazone

Chemical Property:

• Vapor Pressure: 24.2mmHg at 25°C
• Refractive Index: 1.425
• Boiling Point: 110 °C at 760 mmHg
• Flash Point: 20.3 °C
• PSA: 15.60000
• Density: 0.8g/cm³
• LogP: 0.94380
• XLogP3: 0.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 100.100048391
• Heavy Atom Count: 7
• Complexity: 70.1

Purity/Quality:

98%,99%, ^*data from raw suppliers

Acetone Dimethylhydrazone ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R11:
• Hazard Codes: R11:
• Statements: 11
• Safety Statements: 9-16-26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=NN(C)C)C
• Uses: Acetone Dimethylhydrazone is a useful research reagent for hydrazone oxidation, metalation, alkylation and condensation reactions.

Technology Process of Acetone dimethylhydrazone

There total 6 articles about Acetone dimethylhydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

N,N-Dimethylhydrazine (57-14-7) + acetone (67-64-1) → Acetone dimethylhydrazone (13483-31-3)

Guidance literature:

With magnesium sulfate; for 6h; Reflux; Inert atmosphere;

DOI:10.1016/j.tetasy.2015.11.008

Reference yield: 10.3%

1-ethyl-2-(propan-2-ylidene)hydrazine (7422-99-3) + 1,1-dimethyldiazenium bromide (35758-82-8) → Acetone dimethylhydrazone (13483-31-3) + Tetramethyltetrazon (6130-87-6) + 3,3,5,5-tetramethyl-1-ethyl-3,4-dihydroformazan

Guidance literature:

With triethylamine; at -30 - -20 ℃; Title compound not separated from byproducts;

Reference yield:

N,N-Dimethylhydrazine (57-14-7) + acetone (67-64-1) → dimethyl tetrasulfide (5756-24-1) + Dimethyldisulphide (624-92-0) + dimethyltrisulfane (3658-80-8) + bis(dimethylamino)sulfide (2129-20-6) + N,N'-dithiobis-methanamine (928-05-2) + Acetone dimethylhydrazone (13483-31-3) + bis(dimethylamino) trisulfide (5669-44-3) + 1,1-dimethyl-2-thioxohydrazine (13066-27-8) + (dimethylamino) methyl trisulfide (1620476-75-6)

Guidance literature:

With sulfur;

DOI:10.1134/S1070363214060097

upstream raw materials:

N,N-Dimethylhydrazine

acetone

1-ethyl-2-(propan-2-ylidene)hydrazine

1,1-dimethyldiazenium bromide

Downstream raw materials:

3-(Dimethyl-hydrazono)-1,1-diphenyl-butan-1-ol

trans 1-(2-hydroxycyclohexyl)propan-2-one

trans-7-methyl-1,6-dioxaspiro<4.5>decane

(E)-1-Benzylsulfanyl-3-(dimethyl-hydrazono)-but-1-ene-1-thiol

Refernces

• 1、 Lippincott, Daniel J.,Trejo-Soto, Pedro J.,Gallou, Fabrice,Lipshutz, Bruce H.. "Copper-Catalyzed Oxidative Cleavage of Electron-Rich Olefins in Water at Room Temperature". supporting information. p. 5094 - 5097. Retrieved 2018/09/13.
• 2、 Zenkevich,Ul'Yanov,Golub,Buryak. "Chromatographic component of identification of the transformation products of 1,1-dimethylhydrazine in the presence of sulfur". . p. 1106 - 1114. Retrieved 2014/08/05.