9,12-Octadecadienoyl chloride, (9Z,12Z)-

Base Information

• Chemical Name: 9,12-Octadecadienoyl chloride, (9Z,12Z)-
• CAS No.: 7459-33-8
• Molecular Formula: C18H31ClO
• Molecular Weight: 298.897
• Hs Code.: 29130000
• European Community (EC) Number: 231-233-8
• DSSTox Substance ID: DTXSID40864067
• Mol file: 7459-33-8.mol

Synonyms:7459-33-8;9,12-Octadecadienoyl chloride, (9Z,12Z)-;9,12-Octadecadienoyl chloride;octadeca-9,12-dienoyl chloride;octadec-9,12-dienoyl chloride;DTXSID40864067;FBWMYSQUTZRHAT-UHFFFAOYSA-N;AKOS028109103

Chemical Property of 9,12-Octadecadienoyl chloride, (9Z,12Z)-

Chemical Property:

• Appearance/Colour: dark brown liquid or oil
• Vapor Pressure: 5.31E-06mmHg at 25°C
• Refractive Index: 1.47-1.49
• Boiling Point: 380.804 °C at 760 mmHg
• Flash Point: 183.658 °C
• PSA: 17.07000
• Density: 0.93 g/cm³
• LogP: 6.56530
• Storage Temp.: Refrigerator
• XLogP3: 7.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 14
• Exact Mass: 298.2063433
• Heavy Atom Count: 20
• Complexity: 269

Purity/Quality:

98% ^*data from raw suppliers

Linoleoyl Chloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 34
• Safety Statements: 28A-26-45-36/37/39-27

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCCCCC=CCC=CCCCCCCCC(=O)Cl

Technology Process of 9,12-Octadecadienoyl chloride, (9Z,12Z)-

There total 7 articles about 9,12-Octadecadienoyl chloride, (9Z,12Z)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

linoleic acid (60-33-3,116745-32-5,26085-09-6,64080-88-2,7049-66-3,949900-18-9,60476-23-5,6144-28-1,67922-65-0,89718-18-3) → linoleyl chloride (7459-33-8)

Guidance literature:

With oxalyl dichloride; In dichloromethane; at 20 ℃;

DOI:10.1016/S0960-894X(03)00348-2

Reference yield:

oxalyl dichloride (79-37-8) + linoleic acid (60-33-3,116745-32-5,26085-09-6,64080-88-2,7049-66-3,949900-18-9,60476-23-5,6144-28-1,67922-65-0,89718-18-3) → linoleyl chloride (7459-33-8)

Guidance literature:

at 65 - 70 ℃;

DOI:10.1021/ja01230a040

Reference yield:

sodium linoleate (822-17-3) → linoleyl chloride (7459-33-8)

Guidance literature:

With thionyl chloride; at 20 ℃;

DOI:10.1016/S0968-0896(01)00023-2

upstream raw materials:

phosgene

linoleic acid

oxalyl dichloride

sodium linoleate

Downstream raw materials:

cholesterol linoleate

linoleamide

(9Z,12Z)-Octadeca-9,12-dienoic acid 3-[(2-chloro-ethoxy)-(4-nitro-benzyloxy)-phosphoryloxy]-propyl ester

α-Stearoyl-β-linoleoyl-α'-palmitoin

Refernces

• 1、 -. "CATIONIC LIPIDS AND USES THEREOF". Page/Page column 152-153. . Retrieved 2021/01/23.
• 2、 Falasca, Marco,Keating, Damien J.,Kizilkaya, Hüsün Sheyma,Kokh, Elena,Mancera, Ricardo L.,Massi, Massimiliano,Paternoster, Silvano,Rosenkilde, Mette Marie,Simpson, Peter V.. "Pharmacological and structure-activity relationship studies of oleoyl-lysophosphatidylinositol synthetic mimetics". . . Retrieved 2021/08/30.