1,1-Dimethyl-2-selenourea

Base Information

• Chemical Name: 1,1-Dimethyl-2-selenourea
• CAS No.: 5117-16-8
• Molecular Formula: C3H8N2Se
• Molecular Weight: 151.07
• Hs Code.: 2931900090
• European Community (EC) Number: 225-854-3
• NSC Number: 174190
• DSSTox Substance ID: DTXSID3063706
• Mol file: 5117-16-8.mol

Synonyms:Urea,1,1-dimethyl-2-seleno- (6CI,7CI,8CI);1,1-Dimethyl-2-selenourea;1,1-Dimethylselenourea;N,N-Dimethylselenourea;NSC 174190;

Chemical Property of 1,1-Dimethyl-2-selenourea

Chemical Property:

• Appearance/Colour: Light brown to grey crystalline powder
• Melting Point: 172-174 °C
• Boiling Point: 177.2±23.0 °C(Predicted)
• PSA: 29.26000
• LogP: -0.42460
• Storage Temp.: 0-6°C
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 150.97744
• Heavy Atom Count: 6
• Complexity: 59.8

Purity/Quality:

99% ^*data from raw suppliers

1,1-Dimethyl-2-selenourea 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T，N
• Hazard Codes: T,N
• Statements: 23/25-33-50/53
• Safety Statements: 20/21-28-45-60-61-50

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)C(=N)[Se]
• Uses: 1,1-Dimethyl-2-selenourea was used as precursor to synthesize CdSe quantum dots in aqueous solution under simultaneous illumination with a diode-pumped solid state green laser and a Xe-Hg lamp.

Technology Process of 1,1-Dimethyl-2-selenourea

There total 4 articles about 1,1-Dimethyl-2-selenourea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

NCNMe2 (1467-79-4) → N,N-Dimethylselenourea (5117-16-8)

Guidance literature:

NCNMe₂; With hydrogenchloride; In tetrahydrofuran; diethyl ether; at 0 ℃; for 2h;

With LiAlHSeH; In tetrahydrofuran; diethyl ether; at 0 ℃; for 3h;

DOI:10.1016/j.lfs.2004.08.037

Reference yield: 70.0%

dimethylchloroformamidinium chloride → N,N-Dimethylselenourea (5117-16-8)

Guidance literature:

With LiAlHSeH; In tetrahydrofuran; at 0 ℃; for 3h;

DOI:10.1016/S0040-4039(01)01251-5

Reference yield: 9.0%

NCNMe2 (1467-79-4) → N,N-Dimethylselenourea (5117-16-8) + Altretamine (645-05-6) + 1,1-Dimethyl-2-(dimethylselenocarbamoyl)guanidine (130594-29-5) + 3,5-Bis(dimethylamino)-1,2,4-selenadiazole

Guidance literature:

With bis(trimethylsilyl)selenide; boron trifluoride diethyl etherate; In dichloromethane; for 9h; Heating;

DOI:10.1246/cl.1990.1403

upstream raw materials:

NCNMe₂

Downstream raw materials:

4-(2-(dimethylamino)-1,3-selenazol-4-yl)benzonitrile

N,N-dimethyl-4-phenyl-1,3-selenazol-2-amine

2-dimethylamino-5-phenyl-selenazol-4-one

Refernces

• 1、 Takahashi, Hitoe,Nishina, Atsuyoshi,Fukumoto, Ryo-Hei,Kimura, Hirokazu,Koketsu, Mamoru,Ishihara, Hideharu. "Selenoureas and thioureas are effective superoxide radical scavengers in vitro". . p. 2185 - 2192. Retrieved 2007/10/03.
• 2、 Koketsu, Mamoru,Fukuta, Yoshihisa,Ishihara, Hideharu. "Preparation of N,N-unsubstituted selenoureas and thioureas from cyanamides". . p. 6333 - 6335. Retrieved 2007/10/03.