5-Fluorouridine monophosphate

Base Information

• Chemical Name: 5-Fluorouridine monophosphate
• CAS No.: 796-66-7
• Molecular Formula: C₉H₁₂FN₂O₉P
• Molecular Weight: 342.174
• UNII: BMW6RNK254
• DSSTox Substance ID: DTXSID601000617
• Nikkaji Number: J540.442H
• Wikidata: Q27120389
• ChEMBL ID: CHEMBL474163
• Mol file: 796-66-7.mol

Synonyms:5'-FUMP;5-fluorouridine 5'-phosphate;5-fluorouridine 5'-phosphate, 18F-labeled;5-fluorouridine 5'-phosphate, calcium salt;5-fluorouridine 5'-phosphate, disodium salt;5-fluorouridylate;5-fluorouridylic acid;FUMP-5'

Chemical Property of 5-Fluorouridine monophosphate

Chemical Property:

• XLogP3: -3.6
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 4
• Exact Mass: 342.02644512
• Heavy Atom Count: 22
• Complexity: 563

Purity/Quality:

97% ^*data from raw suppliers

5-Fluorouridine-5'-monophosphate sodium salt - 10mM aqueous solution ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(C(=O)NC(=O)N1C2C(C(C(O2)COP(=O)(O)O)O)O)F
• Isomeric SMILES: C1=C(C(=O)NC(=O)N1[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O)F

Technology Process of 5-Fluorouridine monophosphate

There total 2 articles about 5-Fluorouridine monophosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C11H18FN2O15P3 (464169-57-1) → 5-fluorouridine (316-46-1) + 5-fluorouridine 5′-monophosphate (796-66-7,17124-23-1)

Guidance literature:

With ethylenediaminetetraacetic acid; glycine; sodium chloride; In various solvent(s); at 90 ℃; pH=7.5; Further Variations:; Reagents; Temperatures; pH-values; Kinetics;

DOI:10.1021/jo800317e

Reference yield:

C10H16FN2O14P3 → 5-fluorouridine (316-46-1) + 5-fluorouridine 5′-monophosphate (796-66-7,17124-23-1)

Guidance literature:

With sodium acetate; acetic acid; sodium chloride; In various solvent(s); at 90 ℃; pH=5.0; Further Variations:; Reagents; Temperatures; pH-values; Kinetics;

DOI:10.1021/jo800317e

upstream raw materials:

C₁₁H₁₈FN₂O₁₅P₃

Refernces