N,N-Dimethylethylenediamine

Base Information

• Chemical Name: N,N-Dimethylethylenediamine
• CAS No.: 108-00-9
• Molecular Formula: C4H12N2
• Molecular Weight: 88.1527
• Hs Code.: 29212900
• European Community (EC) Number: 203-541-2
• NSC Number: 24506
• UNII: GJ3A38X3M9
• DSSTox Substance ID: DTXSID7059357
• Nikkaji Number: J91.250F
• Wikidata: Q24731206
• Mol file: 108-00-9.mol

Synonyms:N,N-Dimethylethylenediamine;108-00-9;2-Dimethylaminoethylamine;N,N-Dimethyl-1,2-ethanediamine;(2-Aminoethyl)Dimethylamine;2-(Dimethylamino)ethylamine;N,N-Dimethylethanediamine;N1,N1-dimethylethane-1,2-diamine;1,2-Ethanediamine, N,N-dimethyl-;N,N-Dimethyl-1,2-ethylenediamine;N-(2-Aminoethyl)-N,N-dimethylamine;N,N-Dimethyl-1,2-diaminoethane;2-Aminoethyldimethylamine;N,N-Dimethylethane-1,2-diamine;Unsym-dimethylethylenediamine;N',N'-dimethylethane-1,2-diamine;Ethylenediamine, N,N-dimethyl-;NSC 24506;beta-(Dimethylamino)ethylamine;1,2-Ethanediamine, N1,N1-dimethyl-;DMEN;dimethylaminoethylamine;.beta.-(Dimethylamino)ethylamine;EINECS 203-541-2;MFCD00008175;1-Amino-2-dimethylaminoethane;AI3-26641;GJ3A38X3M9;2-(N,N-dimethylamino)ethylamine;N,N-dimethyl-ethane-1,2-diamine;NSC-24506;NSC24506;2dimethylaminoethylamine;2-dimethyaminoethylamine;N-dimethylaminoethylamine;2-dimethylamino-ethylamin;Me2NCH2CH2NH2;2-dimethylamino-ethylamine;2-dimethylaminoethyl amine;N,N-dimethyethylenediamine;N,N-dimethylethlenediamine;N,N-dimethylethylendiamine;2-Dimethylamino ethylamine;n,n dimethylethylenediamine;beta-dimethylaminoethylamine;unsym-dimethyethylenediamine;n,n-dimethyl-ethylendiamine;N,N-dimethlethylene diamine;N,N-dimethyl ethylendiamine;N,N-dimethylethylen-diamine;N,N-dimethyletylene diamine;2-(dimethylamino)ethanamine;unsym dimethylethylenediamine;beta-dimethylamino-ethylamine;N, N-Dimethylethylenediamine;N,N-dimethyl ethylenediamine;N,N-dimethyl-aminoethylamine;N,N-dimethyl-ethylenediamine;N,N-dimethylethyl-enediamine;N,N-dimethylethylene diamine;N,N-dimethylethylene-diamine;UNII-GJ3A38X3M9;(2-aminoethyl) dimethylamine;2-(dimethylamino) ethylamine;2-(dimethylamino)-ethylamine;unsym-dimethylethylene diamine;(N,N-dimethyl)ethylenediamine;N,N-dimethyl ethylene diamine;N,N-dimethyl-ethylene-diamine;DIMETHYLAMINO ETHYLAMINE;n,n-dimethylethan-1,2-diamine;DTXSID7059357;n.n-dimethylethane-1,2-diamine;N, N-dimethyl-1,2-ethanediamine;N, N-dimethylethane-1,2-diamine;N,N-dimethyl ethane-1,2-diamine;2-(N,N-dimethyl-amino)ethylamine;N,N-Dimethylethylenediamine, 95%;N1,N1-dimethyl-1,2-ethanediamine;N1.N1-dimethylethane-1,2-diamine;N',N'-dimethyl-ethane-1,2-diamine;N1, N1-dimethylethane-1,2-diamine;STL183257;N-(2-DIMETHYLAMINOETHYL)AMINE;N1,N1-Dimethyl-ethane-1,2-diamine;AKOS000119882;N,N-METHYL-1,2-ETHANEDIAMINE;N1, N1-dimethyl-ethane-1,2-diamine;SB75354;VS-0322;2-(N,N-DIMETHYLAMINO)ETHANAMINE;1-AMINO-2-(DIMETHYLAMINO)ETHANE;2-N,N-DIMETHYLAMINOETHYLENEDIAMINE;BP-11461;LS-65443;N*1*,N*1*-dimethylethane-1,2-diamine;N*1*,N*1*-dimethyl-ethane-1,2-diamine;AM20080032;D0719;FT-0629531;FT-0667428;EN300-19760;N,N-Dimethylethylenediamine, >=98.0% (GC);S12293;W-108728;Q24731206;F2187-2178

Chemical Property of N,N-Dimethylethylenediamine

Chemical Property:

• Appearance/Colour: colorless liquid
• Vapor Pressure: 0.35 psi ( 20 °C)
• Melting Point: -70 °C
• Refractive Index: n20/D 1.438(lit.)
• Boiling Point: 93.5 °C at 760 mmHg
• PKA: 9.59±0.10(Predicted)
• Flash Point: 23.9 °C
• PSA: 29.26000
• Density: 0.835 g/cm³
• LogP: 0.20700
• Storage Temp.: Flammables area
• Sensitive.: Hygroscopic
• Water Solubility.: MISCIBLE
• XLogP3: -0.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 88.100048391
• Heavy Atom Count: 6
• Complexity: 26.7

Purity/Quality:

99% ^*data from raw suppliers

2-Di ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F,C
• Hazard Codes: T+,F,C
• Statements: 24/25-26-34-35-21/22-11-36/37-10
• Safety Statements: 26-28-36/37/39-45-36-28A-23-16

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)CCN
• Uses: It finds its application as an intermediate in the synthesis of Cefotiam. It is also used as a catalyst in the synthesis of allylic nitro compounds. N,N-Dimethylethylenediamine is a bidentate ligand that can be used:To synthesize Schiff base ligands to prepare their zinc alkyl and zinc alkoxide complexes that initiate ring-opening polymerization of lactides.As a ligand to prepare copper azido polymers.In the synthesis of naphthalimides such as amonafide, an antitumor agent.As the receptor in building fluorescent signaling systems to perturb the photoinduced intramolecular electron transfer (PET) process from the nitrogen lone-pair to the fluorophore.

Technology Process of N,N-Dimethylethylenediamine

There total 24 articles about N,N-Dimethylethylenediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.82%

→ N,N-dimethylethylenediamine (108-00-9)

Guidance literature:

With ammonia; In methanol; at 25 ℃; for 12h;

Reference yield: 79.0%

4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl-amine (383865-57-4) → 1-(2-Dimethylamino-ethyl)-3-(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-urea + N,N-dimethylethylenediamine (108-00-9)

Guidance literature:

Reference yield: 40.0%

ethyleneimine (151-56-4,9002-98-6) + dimethyl amine (124-40-3) → N,N-dimethylethylenediamine (108-00-9)

Guidance literature:

In methanol; 1.) 20 deg C, 12 h, 2.) reflux, 12 h;

DOI:10.1007/BF00962346

upstream raw materials:

ethyleneimine

dimethyl amine

2-(2-bromoethyl)isoindoline-1,3-dione

N-<2-(dimethylamino)ethyl>phthalimide

Downstream raw materials:

N,N-dimethyl-N'-(pyridine-2-yl)ethane-1,2-diamine

N'-(1-ethyl-[3]piperidyl)-N,N-dimethyl-ethylenediamine

N-<2-(dimethylamino)ethyl>phthalimide

phenyl(2-pyridinyl)methanol

Refernces

• 1、 Alekperov, R. K.,Kostyanovskii, R. G.. "N-β-DIMETHYLAMINOETHYLURETHYLANE AS A CHEMICAL MUTAGEN WITH POSSIBLE CARBAMOYLATING ACTION". . p. 873 - 874. Retrieved 1987.
• 2、 Turner. "-". . p. 1607. Retrieved 1946.
• 3、 -. "Two-photon fluorescent probe for detecting nitric oxide near cell membranes". Paragraph 0014. . Retrieved 2018/03/28.
• 4、 Wang, Wenwen,Wei, Ruisong,Yin, Guohui,Tian, Jun,Duan, Yifan,Chen, Ligong,Li, Yang. "The synthesis of asymmetric ethylenediamine derivatives catalyzed by ion-exchange resins". . p. 4511 - 4522. Retrieved 2015/06/30.