N-(2-Hydroxy-3,5-dinitrophenyl)acetamide

Base Information

• Chemical Name: N-(2-Hydroxy-3,5-dinitrophenyl)acetamide
• CAS No.: 5422-72-0
• Molecular Formula: C8H7 N3 O6
• Molecular Weight: 241.16
• Hs Code.: 2924299090
• European Community (EC) Number: 226-547-7
• NSC Number: 10048
• UNII: M9YEG822FE
• DSSTox Substance ID: DTXSID5063863
• Nikkaji Number: J27.350C
• Wikidata: Q81991058
• Mol file: 5422-72-0.mol

Synonyms:N-(2-Hydroxy-3,5-dinitrophenyl)acetamide;5422-72-0;3',5'-Dinitro-2'-hydroxyacetanilide;Acetamide, N-(2-hydroxy-3,5-dinitrophenyl)-;3',5'-Dinitro-2'-hydroxyacetaniline;Acetanilide, 2'-hydroxy-3',5'-dinitro-;Acetamide, N-(3,5-dinitro-2-hydroxyphenyl)-;EINECS 226-547-7;NSC 10048;NSC-10048;ACETAMIDE,N-(2-HYDROXY-3,5-DINITROPHENYL)-;NSC10048;Acetanilide,5'-dinitro-;Acetamide,5-dinitrophenyl)-;M9YEG822FE;DTXSID5063863;RMWYWQJCJOEMTR-UHFFFAOYSA-N;2-(Acetylamino)-4,6-dinitrophenol;STK662711;AKOS037631810;Acetamide,5-dinitro-2-hydroxyphenyl)-;N-(2-Hydroxy-3,5-dinitrophenyl)acetamide #;AE-562/05002029

Chemical Property of N-(2-Hydroxy-3,5-dinitrophenyl)acetamide

Chemical Property:

• Vapor Pressure: 1.89E-07mmHg at 25°C
• Boiling Point: 414.2°Cat760mmHg
• Flash Point: 204.3°C
• PSA: 140.97000
• Density: 1.667g/cm³
• LogP: 2.28640
• XLogP3: 1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 1
• Exact Mass: 241.03348495
• Heavy Atom Count: 17
• Complexity: 335

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)NC1=C(C(=CC(=C1)[N+](=O)[O-])[N+](=O)[O-])O

Technology Process of N-(2-Hydroxy-3,5-dinitrophenyl)acetamide

There total 17 articles about N-(2-Hydroxy-3,5-dinitrophenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

acetyl chloride (75-36-5) + picramic acid (96-91-3) → acetic acid-(2-hydroxy-3,5-dinitro-anilide) (5422-72-0)

Guidance literature:

With benzene;

DOI:10.1021/ja01271a048

Reference yield:

acetic anhydride (108-24-7) + picramic acid (96-91-3) → acetic acid-(2-amino-4,6-dinitro-phenyl ester) + acetic acid-(2-hydroxy-3,5-dinitro-anilide) (5422-72-0)

Guidance literature:

With sulfuric acid;

DOI:10.1021/ja01271a048

Reference yield:

acetic anhydride (108-24-7) + picramic acid (96-91-3) → acetic acid-(2-hydroxy-3,5-dinitro-anilide) (5422-72-0)

Guidance literature:

upstream raw materials:

N,N,O-Triacetyl-2-aminophenol

2-acetamidophenyl acetate

acetic acid-(2,3,5-trinitro-anilide)

acetic anhydride

Downstream raw materials:

N-acetyl-N-(2-hydroxy-3,5-dinitro-phenyl)-β-D-glucopyranosylamine

N,O²,O³,O⁴,O⁶-pentaacetyl-N-(2-hydroxy-3,5-dinitro-phenyl)-β-D-glucopyranosylamine

tetra-O-acetyl-N-(2-hydroxy-3,5-dinitro-phenyl)-N-methyl-β-D-glucopyranosylamine

2-methylamino-4,6-dinitro-phenol