4-Aminofluorene

Base Information

• Chemical Name: 4-Aminofluorene
• CAS No.: 7083-63-8
• Molecular Formula: C13H11N
• Molecular Weight: 181.237
• NSC Number: 90664
• UNII: 5SYU175X98
• DSSTox Substance ID: DTXSID10221082
• Nikkaji Number: J3.094E
• Wikidata: Q26840864
• Mol file: 7083-63-8.mol

Synonyms:4-Aminofluorene;9H-Fluoren-4-amine;7083-63-8;FLUOREN-4-AMINE;CCRIS 6999;NSC 90664;BRN 2093504;AI3-50520;5SYU175X98;NSC-90664;NSC90664;9H-fluoren-4-ylamine;AMINOFLUORENE, 4-;NCIOpen2_001486;UNII-5SYU175X98;SCHEMBL2048985;DTXSID10221082;LS-69160;FT-0720479;Q26840864

Chemical Property of 4-Aminofluorene

Chemical Property:

• Vapor Pressure: 5.92E-06mmHg at 25°C
• Refractive Index: 1.697
• Boiling Point: 379.3 °C at 760 mmHg
• PKA: 4.09±0.20(Predicted)
• Flash Point: 204.8 °C
• PSA: 26.02000
• Density: 1.203 g/cm³
• LogP: 3.42120
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 181.089149355
• Heavy Atom Count: 14
• Complexity: 213

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1C2=C(C3=CC=CC=C31)C(=CC=C2)N

Technology Process of 4-Aminofluorene

There total 8 articles about 4-Aminofluorene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-nitrofluorene (24237-68-1) → 4-Aminofluorene (7083-63-8)

Guidance literature:

With ethanol; calcium chloride; zinc;

DOI:10.1021/ja01138a024

Reference yield:

4-Ethoxycarbonylamino-fluoren (500545-92-6) → 4-Aminofluorene (7083-63-8)

Guidance literature:

With potassium hydroxide;

DOI:10.1021/jo01258a083

Reference yield:

fluorene-4-carboxylic acid chloride (7315-93-7) → 4-Aminofluorene (7083-63-8)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) NaN₃, (ii) (heating), benzene, (iii) /BRN= 1718733/

2: aq. KOH

With potassium hydroxide;

DOI:10.1021/jo01258a083

upstream raw materials:

fluorene-4-carboxylic acid

4-nitrofluorene

methyl 4-fluorenecarboxylate

4-Ethoxycarbonylamino-fluoren

Downstream raw materials:

4-acetylaminofluorene

4-Nitroso-fluoren

4-Brom-fluoren-9-carbonsaeure

4-bromophenanthrene