17 alpha-ethynylestradiol-17 beta-D-glucopyranosiduronic acid

Base Information

• Chemical Name: 17 alpha-ethynylestradiol-17 beta-D-glucopyranosiduronic acid
• CAS No.: 75803-39-3
• Molecular Formula: C26H32 O8
• Molecular Weight: 472.535
• Mol file: 75803-39-3.mol

Synonyms:19-Norpregnane,b-D-glucopyranosiduronic acidderiv.

Chemical Property of 17 alpha-ethynylestradiol-17 beta-D-glucopyranosiduronic acid

Chemical Property:

• Vapor Pressure: 1.56E-20mmHg at 25°C
• Melting Point: 156-158°C
• Boiling Point: 699.4°C at 760 mmHg
• Flash Point: 236.5°C
• PSA: 136.68000
• Density: 1.44g/cm³
• LogP: 1.52910
• Storage Temp.: -20°C Freezer

Purity/Quality:

98% ^*data from raw suppliers

EthynylEstradiol17-β-D-Glucuronide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 17 alpha-ethynylestradiol-17 beta-D-glucopyranosiduronic acid

There total 2 articles about 17 alpha-ethynylestradiol-17 beta-D-glucopyranosiduronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

mestranol (72-33-3) → ethinyl estradiol (57-63-6) + 2-hydroxy-mestranol (26011-40-5) + 17a-Ethynyl-2-methoxyestradiol (22415-44-7,26011-46-1) + [3H]-Ethinylestradiol glucuronide (60134-76-1) + 17-ethynyl-3-hydroxy-1,2,3(10)-estratrien-17β-yl-β-D-glucopyranosiduronate (75803-39-3) + 17-ethynyl-1,2,3(10)-estratrien-3,17β-diyl-β-D-glucopyranosiduronate (75812-41-8)

Guidance literature:

Product distribution; metabolism in women in dependence on geographic locality;

DOI:10.1016/0039-128X(80)90001-X

Reference yield:

ethinyl estradiol (57-63-6) → 17-ethynyl-3-hydroxy-1,3,5(10)-estratrien-17β-yl-sulfate (75803-36-0) + ethynyl estradiol 3-sulfate (24560-70-1) + 17-ethynyl-1,3,5(10)-estratrien-3,17β-diyl-disulfate (75803-37-1) + [3H]-Ethinylestradiol glucuronide (60134-76-1) + 17-ethynyl-3-hydroxy-1,2,3(10)-estratrien-17β-yl-β-D-glucopyranosiduronate (75803-39-3) + 17-ethynyl-1,2,3(10)-estratrien-3,17β-diyl-β-D-glucopyranosiduronate (75812-41-8)

Guidance literature:

Product distribution; metabolism in women in dependence on geographic locality;

DOI:10.1016/0039-128X(80)90001-X

upstream raw materials:

mestranol

ethinyl estradiol

Refernces