Magnesium, chloro(1-methylethyl)-

Base Information

• Chemical Name: Magnesium, chloro(1-methylethyl)-
• CAS No.: 1068-55-9
• Molecular Formula: C3H7ClMg
• Molecular Weight: 102.847
• Hs Code.: 29319090
• European Community (EC) Number: 213-947-1
• UNII: MN8G5FEJ5J
• DSSTox Substance ID: DTXSID6061444
• Wikipedia: Isopropylmagnesium_chloride
• Mol file: 1068-55-9.mol

Synonyms:Isopropylmagnesium Chloride;1068-55-9;Magnesium, chloro(1-methylethyl)-;Chloro(1-methylethyl)magnesium;isopropyl magnesium chloride;i-PrMgCl;Chloroisopropylmagnesium;2-Propylmagnesium chloride;MN8G5FEJ5J;MFCD00000466;isopropylmagnesiumchloride;Isopropylmagnesium chloride, 2.0 M in THF;Isopropylmagnesium chloride, 1.0 M in 2-MeTHF;Magnesium, chloroisopropyl- (7CI,8CI);Chloro(propan-2-yl)magnesium;i-propylmagnesium chloride;iPrMgCl;iPr-MgCl;EINECS 213-947-1;i-propylmagnesiumchloride;isopropylmagnesium chlorid;isopropymagnesium chloride;UNII-MN8G5FEJ5J;Chloro(isopropyl)magnesium;Chloro-isopropyl-magnesium;isopropyl magnesiumchloride;isopropylmagnesium-chloride;i-propyl magnesium chloride;EC 213-947-1;iso-Propylmagnesium chloride;isopropyl-magnesium chloride;2-propyl magnesium chloride;SCHEMBL4892;iso-propyl magnesium chloride;iso-propyl-magnesium chloride;iso-propyl-magnesium-chloride;DTXSID6061444;GPIBKUJXKCEZOH-UHFFFAOYSA-M;MAGNESIUM, CHLOROISOPROPYL-;AMY40195;AKOS015909147;Isopropyl magnesium chloride 2M in THF;Isopropylmagnesium chloride, 1M in MeTHF;i-Propylmagnesium chloride, 2-3M in ether;Isopropyl magnesium chloride 2M in diethyl ether;Isopropylmagnesium Chloride (13% in Ethyl Ether, ca. 1mol/L);Isopropylmagnesium Chloride (ca. 13% in Ethyl Ether, ca. 1mol/L);Isopropylmagnesium Chloride (ca. 11% in Tetrahydrofuran, ca. 1mol/L)

Chemical Property of Magnesium, chloro(1-methylethyl)-

Chemical Property:

• Appearance/Colour: powder
• Melting Point: 155-157 °C
• Boiling Point: 256 °C
• Flash Point: 72 °F
• PSA: 0.00000
• Density: 0.98 g/mL at 20 °C
• LogP: 2.05350
• Storage Temp.: Flammables + water-Freezer (-20°C)e area
• Sensitive.: Air & Moisture Sensitive
• Water Solubility.: It reacts violently with water.
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 102.0086696
• Heavy Atom Count: 5
• Complexity: 6.9

Purity/Quality:

Purity greater than 99.5% ^*data from raw suppliers

IsopropylmagnesiumChloride(2MinTHF) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C, F+, F
• Hazard Codes: C,F+,F
• Statements: 12-14/15-19-22-34-66-67-14-10-11-37
• Safety Statements: 26-36/37/39-43-45-16-33-9

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Metals -> Metals, Organic Compounds
• Canonical SMILES: C[CH-]C.[Mg+2].[Cl-]
• Uses: Isopropylmagnesium Chloride is a grignard reagent that can be used in the transmetalation of grignard reagents to make versatile org. semiconductors.

Technology Process of Magnesium, chloro(1-methylethyl)-

There total 7 articles about Magnesium, chloro(1-methylethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

isopropyl chloride (75-29-6) → isopropylmagnesium chloride (1068-55-9)

Guidance literature:

With magnesium; In tetrahydrofuran-d8; at 80 ℃; under 5171.62 Torr; Temperature; Concentration; Inert atmosphere; Flow reactor;

DOI:10.3762/bjoc.16.115

Reference yield:

→ 3,5-dimethylbenzaldehyde (5779-95-3) + isopropylmagnesium chloride (1068-55-9)

Guidance literature:

Reference yield:

C11H19NO4 (1194059-56-7) + C17H33NO4Si (1194059-55-6) + dimethyl 1-(1-diazo-2-oxopropyl)phosphonate (90965-06-3) → C18H33NO3Si (1194059-57-8) + isopropylmagnesium chloride (1068-55-9)

Guidance literature:

dimethyl 1-(1-diazo-2-oxopropyl)phosphonate; With 4-toluenesulfonyl azide; potassium carbonate; In acetonitrile; at 0 - 20 ℃; for 2h; Inert atmosphere; Cooling with ice bath;

C₁₁H₁₉NO₄; C₁₇H₃₃NO₄Si; In methanol; acetonitrile; at 20 ℃; Inert atmosphere;

upstream raw materials:

isopropyl chloride

magnesium

C₁₁H₁₉NO₄

C₁₇H₃₃NO₄Si

Downstream raw materials:

N-benzyl-N-isopropylhydroxylamine

1-benzo[1,3]dioxol-5-yl-2-methyl-propan-1-ol

styryl-malonic acid

(2-bromophenyl)malonic acid

Refernces

• 1、 Schnegelsberg, Christoph,Bachmann, Sebastian,Kolter, Marlene,Auth, Thomas,John, Michael,Stalke, Dietmar,Koszinowski, Konrad. "Association and Dissociation of Grignard Reagents RMgCl and Their Turbo Variant RMgC?LiCl". . p. 7752 - 7762. Retrieved 2016.
• 2、 Deitmann, Eva,G?ssl, Lars,Hofmann, Christian,L?b, Patrick,Menges-Flanagan, Gabriele. "Scalable Continuous Synthesis of Grignard Reagents from in Situ-Activated Magnesium Metal". . p. 315 - 321. Retrieved 2020/03/10.