2-Bromo-N-phenylbenzamide

Base Information

• Chemical Name: 2-Bromo-N-phenylbenzamide
• CAS No.: 10282-57-2
• Molecular Formula: C13H10 Br N O
• Molecular Weight: 276.132
• Hs Code.: 2924299090
• DSSTox Substance ID: DTXSID20145523
• Nikkaji Number: J570.613K
• Wikidata: Q27163868
• ChEMBL ID: CHEMBL1708490
• Mol file: 10282-57-2.mol

Synonyms:2-BROMO-N-PHENYLBENZAMIDE;10282-57-2;Benzamide, 2-bromo-N-phenyl-;AI3-01074;2-Bromo-N-phenyl-benzamide;2-bromobenzanilide;Cambridge id 5306995;MLS002699909;SCHEMBL882734;CHEMBL1708490;CHEBI:92073;DTXSID20145523;BHHGABOCAHPYMA-UHFFFAOYSA-N;AKOS000177441;SMR001563711;AB00079774-01;SR-01000203790;SR-01000203790-1;BRD-K04156788-001-01-7;Q27163868;Z27782610

Chemical Property of 2-Bromo-N-phenylbenzamide

Chemical Property:

• Vapor Pressure: 0.000769mmHg at 25°C
• Boiling Point: 306.5°Cat760mmHg
• Flash Point: 139.2°C
• PSA: 32.59000
• Density: 1.496g/cm³
• LogP: 4.08540
• XLogP3: 3.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 274.99458
• Heavy Atom Count: 16
• Complexity: 238

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Bromo-N-phenylbenzamide 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)NC(=O)C2=CC=CC=C2Br

Technology Process of 2-Bromo-N-phenylbenzamide

There total 15 articles about 2-Bromo-N-phenylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-bromobenzoic acid chloride (7154-66-7) + aniline (62-53-3) → 2-bromobenzanilide (10282-57-2)

Guidance literature:

With pyridine; dmap; at 0 - 20 ℃;

Reference yield: 93.0%

N’-((2-bromophenyl)-(phenyl)methylene)-4-methylbenzenesulfonohydrazide (105941-87-5) → 2-bromobenzanilide (10282-57-2)

Guidance literature:

Reference yield: 83.0%

o-cyanobromobenzene (2042-37-7) + phenylboronic acid (98-80-6) → 2-bromobenzanilide (10282-57-2)

Guidance literature:

With potassium tert-butylate; copper(ll) bromide; In tert-butyl alcohol; at 20 ℃; for 35h;

DOI:10.1055/s-0036-1588373

upstream raw materials:

2-bromobenzophenone oxime

2-bromobenzoic acid chloride

aniline

2-bromobenzoic-acid

Downstream raw materials:

2-bromo-4'-dimethylamino-benzophenone

(2-Bromo-benzoyl)-phenyl-carbamic acid isopropyl ester

N-[1-(2-Bromo-phenyl)-1-phenylamino-meth-(E)-ylidene]-benzenesulfonamide

N-[1-(2-Bromo-phenyl)-1-phenylamino-meth-(E)-ylidene]-4-chloro-benzenesulfonamide

Refernces

• 1、 Qiao, Yan,Li, Gaoqiang,Liu, Sha,Yangkai, Yujie,Tu, Jingxuan,Xu, Feng. "Synthesis of N -Aryl Amides by Ligand-Free Copper-Catalyzed ipso -Amidation of Arylboronic Acids with Nitriles". . p. 1834 - 1838. Retrieved 2017.
• 2、 Wang, Yi-Jie,Zhang, Guo-Yu,Shoberu, Adedamola,Zou, Jian-Ping. "Iron-catalyzed oxidative amidation of acylhydrazines with amines". supporting information. . Retrieved 2021/08/18.
• 3、 -. "Method for synthesizing amide compound through photocatalysis in water phase". Paragraph 0018-0028. . Retrieved 2019/10/01.