Glycylvaline

Base Information

• Chemical Name: Glycylvaline
• CAS No.: 2325-17-9
• Molecular Formula: C7H14N2O3
• Molecular Weight: 174.2
• Hs Code.: 2924199090
• European Community (EC) Number: 217-806-5
• NSC Number: 163327,522444,122051,206264,83255
• DSSTox Substance ID: DTXSID601316551
• ChEMBL ID: CHEMBL1221782
• Mol file: 2325-17-9.mol

Synonyms:Gly-Val;glycyl-L-valine;glycylvaline;glycylvaline, (D)-isomer;glycylvaline, (L)-isomer

Chemical Property of Glycylvaline

Chemical Property:

• Melting Point: 173-174 °C
• Boiling Point: 405 °C at 760 mmHg
• PKA: 3.17±0.10(Predicted)
• Flash Point: 198.8 °C
• PSA: 92.42000
• Density: 1.168 g/cm³
• LogP: 0.26170
• Storage Temp.: -15°C
• XLogP3: -2.7
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 174.10044231
• Heavy Atom Count: 12
• Complexity: 180

Purity/Quality:

99%+, ^*data from raw suppliers

2-(2-Aminoacetamido)-3-methylbutanoicacid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)C(C(=O)O)NC(=O)CN

Technology Process of Glycylvaline

There total 11 articles about Glycylvaline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

racemic N-chloroacetylvaline (4090-17-9) → Glycylvaline (2325-17-9,6491-59-4)

Guidance literature:

With ammonia; at 38 ℃; N-glycyl-DL-valine;

Reference yield:

→ Glycylvaline (2325-17-9,6491-59-4)

Guidance literature:

With ethanol; palladium; at 70 ℃; Hydrogenation;

Reference yield:

→ Glycylvaline (2325-17-9,6491-59-4)

Guidance literature:

With ammonia; water;

upstream raw materials:

2-thioxo-thiazolidin-5-one

D,L-valine

racemic N-chloroacetylvaline

N-(N,N-phthaloyl-glycyl)-DL-valine

Downstream raw materials:

3-isopropyl-piperazine-2,5-dione

N-(N-chloroacetyl-glycyl)-valine

2-[2-[(E)-4-Dimethylamino-phenylimino]-2-(6-hydroxy-2,7-dimethoxy-1,4-dioxo-1,4-dihydro-carbazol-9-yl)-acetylamino]-3-methyl-butyric acid

N-benzyloxycarbonyl-phenylalanyl=>glycyl=>valine ethyl ester; N-benzyloxycarbonyl-D-phenylalanyl=>glycyl=>D-valine ethyl ester

Refernces