N,N-DIETHYL-2,3,3,3-TETRAFLUOROPROPIONAMIDE

Base Information

• Chemical Name: N,N-DIETHYL-2,3,3,3-TETRAFLUOROPROPIONAMIDE
• CAS No.: 392-63-2
• Molecular Formula: C7H11 F4 N O
• Molecular Weight: 201.164
• Hs Code.: 2924199090
• Mol file: 392-63-2.mol

Synonyms:Propionamide,N,N-diethyl-2,3,3,3-tetrafluoro- (6CI,8CI);N,N-Diethyl-2,3,3,3-tetrafluoropropanamide; N,N-Diethyl-2,3,3,3-tetrafluoropropionamide

Chemical Property of N,N-DIETHYL-2,3,3,3-TETRAFLUOROPROPIONAMIDE

Chemical Property:

• Vapor Pressure: 0.676mmHg at 25°C
• Refractive Index: 1.392
• Boiling Point: 211.3°Cat760mmHg
• PKA: -1.33±0.70(Predicted)
• Flash Point: 81.6°C
• PSA: 20.31000
• Density: 1.178g/cm³
• LogP: 1.75520
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

N,N-Diethyl-2,3,3,3-tetrafluoropropionamide ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N,N-DIETHYL-2,3,3,3-TETRAFLUOROPROPIONAMIDE

There total 1 articles about N,N-DIETHYL-2,3,3,3-TETRAFLUOROPROPIONAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

hexafluoropropene-diethylamine adduct (309-88-6) + 1,3-cylohexanedione (504-02-9) → N,N'-diethyl-1,2,2,2-tetrafluoropropionamide (392-63-2) + 2-(2,3,3,3-tetrafluoropropanoyl)-1,3-cyclohexanedione

Guidance literature:

In dichloromethane; at 2 - 20 ℃; for 48h; Inert atmosphere;

DOI:10.1016/j.jfluchem.2011.06.011

Reference yield: 99.0%

methanol (67-56-1) + N,N'-diethyl-1,2,2,2-tetrafluoropropionamide (392-63-2) → methyl 2,3,3,3-tetrafluoropropanoate (382-93-4)

Guidance literature:

With hydrogenchloride; In water; at 130 ℃; for 10h; Reagent/catalyst; Solvent; Temperature; Catalytic behavior;

Reference yield: 98.1%

N,N'-diethyl-1,2,2,2-tetrafluoropropionamide (392-63-2) → diethylamine (109-89-7) + 2,3,3,3-Tetrafluoropropanol-1

Guidance literature:

With aluminum (III) chloride; zinc borohydride; In methanol; at 60 ℃; for 10h; Reagent/catalyst; Temperature; Solvent;

upstream raw materials:

hexafluoropropene-diethylamine adduct

1,3-cylohexanedione

Downstream raw materials:

threo-(E)-N,N-diethyl-2-fluoro-3-hydroxy-5-phenyl-2-trifluoromethyl-4-pentenamide

threo-N,N-diethyl-2-fluoro-3-hydroxy-3-(p-tolyl)-2-trifluoromethylpropanamide

2-[(4-Chloro-phenyl)-hydroxy-methyl]-N,N-diethyl-2,3,3,3-tetrafluoro-propionamide

threo-N,N-diethyl-2-fluoro-3-(4-chlorophenyl)-3-hydroxy-2-trifluoromethylpropanamide

Refernces