Corosin

Base Information

• Chemical Name: Corosin
• CAS No.: 53527-49-4
• Molecular Formula: C30H46O7
• Molecular Weight: 518.682
• NSC Number: 144943
• DSSTox Substance ID: DTXSID80301608
• Wikidata: Q82045742
• Mol file: 53527-49-4.mol

Synonyms:Corosin;53527-49-4;Capsularone;Vismiaefolic acid;2,3,19-trihydroxyurs-12-ene-23,28-dioic acid;Trachelosperogenin A;2,3,12-trihydroxy-4,6a,6b,11,12,14b-hexamethyl-1,2,3,4a,5,6,7,8,9,10,11,12a,14,14a-tetradecahydropicene-4,8a-dicarboxylic acid;DTXSID80301608;CHEBI:167968;NSC144943;NSC-144943

Chemical Property of Corosin

Chemical Property:

• Vapor Pressure: 8.05E-21mmHg at 25°C
• Boiling Point: 670.1°Cat760mmHg
• Flash Point: 373°C
• PSA: 135.29000
• Density: 1.28g/cm³
• LogP: 4.23990
• XLogP3: 4.2
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 2
• Exact Mass: 518.32435380
• Heavy Atom Count: 37
• Complexity: 1050

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)C(=O)O)O)O)C)C)C2C1(C)O)C)C(=O)O

Technology Process of Corosin

There total 3 articles about Corosin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

28-O-[β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl]-2α,3β,19α-trihydroxyurs-12-ene-24,28-dioic acid → 2α,3β,19α-Trihydroxy-12-ursen-24,28-dicarbonsaeure (53527-49-4)

Guidance literature:

With hydrogenchloride; water; at 90 ℃; for 1h;

DOI:10.5935/0103-5053.20150113

Reference yield:

trachelosperoside A-1 (109750-36-9) → 2α,3β,19α-Trihydroxy-12-ursen-24,28-dicarbonsaeure (53527-49-4)

Guidance literature:

With sodium hydroxide; for 0.166667h; Heating;

DOI:10.1002/ardp.19943271008

Reference yield:

Coreanogenoic acid (132302-48-8) → 2α,3β,19α-trihydroxyurs-12-ene-23,28-dioic acid (53527-49-4,132282-70-3) + 2α,3α,19α,23-tetrahydroxyurs-12-ene-24,28-dioic acid (109750-35-8,132282-71-4)

Guidance literature:

With ethanol; potassium carbonate; for 4h; Heating;

DOI:10.1016/0031-9422(90)80199-Q

upstream raw materials:

trachelosperoside A-1

Coreanogenoic acid

Downstream raw materials:

Methyl-23-hydroxy-tormentat

Refernces

• 1、 Romussi,Parodi,Pizza,De Tommasi. "Constituents of fagaceae (Cupuliferae). XIX: Triterpene saponins and acylated flavonoids from Quercus robur L. var. stenocarpa Beck.". . p. 643 - 645. Retrieved 1994.
• 2、 Ohtani, Kazuhiro,Miyajima, Chikako,Takahasi, Tomoko,Kasai, Ryoji,Tanaka, Osamu,et al.. "A DIMERIC TRITERPENE-GLYCOSIDE FROM RUBUS COREANUS". . p. 3275 - 3280. Retrieved 2007/10/02.