ethyl 4-aMino-3,5-diMethylbenzoate

Base Information

• Chemical Name: ethyl 4-aMino-3,5-diMethylbenzoate
• CAS No.: 3095-47-4
• Molecular Formula: C11H15NO2
• Molecular Weight: 193.246
• Hs Code.: 2922499990
• Mol file: 3095-47-4.mol

Synonyms:2,6-Xylidine-4-carboxylicacid ethyl ester;3,5-Dimethyl-4-aminobenzoic acid ethyl ester;Ethyl 3,5-dimethyl-4-aminobenzoate;Ethyl 4-amino-3,5-dimethylbenzoate;

Chemical Property of ethyl 4-aMino-3,5-diMethylbenzoate

Chemical Property:

• Vapor Pressure: 6.83E-05mmHg at 25°C
• Refractive Index: 1.545
• Boiling Point: 343.9 °C at 760 mmHg
• Flash Point: 190.5 °C
• PSA: 52.32000
• Density: 1.081 g/cm³
• LogP: 2.64350

Purity/Quality:

99% ^*data from raw suppliers

Benzoicacid,4-amino-3,5-dimethyl-,ethylester 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ethyl 4-aMino-3,5-diMethylbenzoate

There total 6 articles about ethyl 4-aMino-3,5-diMethylbenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,5-dimethyl-4-nitrobenzoic acid ethyl ester (3095-50-9) → 4-amino-3,5-dimethylbenzoic acid ethyl ester (3095-47-4)

Guidance literature:

palladium-carbon; In ethyl acetate;

Reference yield:

C16H23NO4 → 4-amino-3,5-dimethylbenzoic acid ethyl ester (3095-47-4)

Guidance literature:

With hydrogenchloride; In water; at 110 ℃; for 1h; under 1520.1 Torr;

Reference yield:

3,5-dimethyl-4-nitrobenzoic acid (3095-38-3) → 4-amino-3,5-dimethylbenzoic acid ethyl ester (3095-47-4)

Guidance literature:

Multi-step reaction with 2 steps

1: ferrosulfate; concentrated ammonia

2: alcoholic KOH-solution

With potassium hydroxide; ammonia; iron(II) sulfate;

upstream raw materials:

3,5-dimethyl-4-nitrobenzoic acid

3,5-dimethyl-4-nitrobenzoic acid ethyl ester

1-amino-2-methylbenzene-4-carboxylic acid ethyl ester

Downstream raw materials:

3,5-dimethyl-4-(2',6'-dimethylphenylazo)benzoic acid

3,5-dimethyl-4-phenylazobenzoic acid ethyl ester

2,6-dimethylaniline

Refernces

• 1、 -. "Substituted benzamides with activity towards EP4 receptors". . . Retrieved 2014/08/20.
• 2、 Nishioka, Hidenori,Liang, Xingguo,Asanuma, Hiroyuki. "Effect of the ortho modification of azobenzene on the photoregulatory efficiency of DNA hybridization and the thermal stability of its eis form". supporting information; experimental part. p. 2054 - 2062. Retrieved 2010/07/05.