BUTANOICACID,4-BUTOXY-

Base Information

• Chemical Name: BUTANOICACID,4-BUTOXY-
• CAS No.: 55724-73-7
• Molecular Formula: C₈H₁₆O₃
• Molecular Weight: 160.213
• Mol file: 55724-73-7.mol

Synonyms:4-Butoxybutanoicacid; 4-Butoxybutyric acid

Chemical Property of BUTANOICACID,4-BUTOXY-

Chemical Property:

• Vapor Pressure: 0.00312mmHg at 25°C
• Boiling Point: 262.9°Cat760mmHg
• PKA: 4?+-.0.10(Predicted)
• Flash Point: 100°C
• PSA: 46.53000
• Density: 0.991g/cm³
• LogP: 1.66790

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of BUTANOICACID,4-BUTOXY-

There total 5 articles about BUTANOICACID,4-BUTOXY- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Butoxyethanol (111-76-2,9004-77-7) → 4-butoxybutanoic acid (55724-73-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 157 g / PBr₃ / pyridine; diethyl ether / 1) -15 deg C, 0.5 h, 2) reflux, 2 h

2: 1) EtONa, 2) KOH / 1) EtOH, 85 - 90 deg C, 4 h, 2) water, reflux, 4 h

3: 91 g / 4 h / 120 - 130 °C

With potassium hydroxide; sodium ethanolate; phosphorus tribromide; In pyridine; diethyl ether;

DOI:10.1016/0039-128X(83)90099-5

Reference yield:

2-(2-Butoxy-ethyl)-malonic acid (88663-61-0) → 4-butoxybutanoic acid (55724-73-7)

Guidance literature:

at 120 - 130 ℃; for 4h;

DOI:10.1016/0039-128X(83)90099-5

Reference yield:

1-(2-bromoethoxy)butane (6550-99-8) → 4-butoxybutanoic acid (55724-73-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 1) EtONa, 2) KOH / 1) EtOH, 85 - 90 deg C, 4 h, 2) water, reflux, 4 h

2: 91 g / 4 h / 120 - 130 °C

With potassium hydroxide; sodium ethanolate;

DOI:10.1016/0039-128X(83)90099-5

upstream raw materials:

(2-Butoxyethyl)malonsaeure-diethylester

4-(4-nitrophenoxy)butanoic acid

sodium butanolate

2-(2-Butoxy-ethyl)-malonic acid

Downstream raw materials:

butyl 4-chlorobutyrate

Refernces