NAPHTHO[2,1-B]FURAN-2(1H)-ONE

Base Information

• Chemical Name: NAPHTHO[2,1-B]FURAN-2(1H)-ONE
• CAS No.: 4352-63-0
• Molecular Formula: C12H8O2
• Molecular Weight: 184.194
• Hs Code.: 2932999099
• Mol file: 4352-63-0.mol

Synonyms:hydronaphtho[2,1-b]furan-2-one;naphthobfuranone;2-Hydroxy-1-naphthaleneacetic acid lactone;Naphtho[2,1-b]furan-2(1H)-one;1H-Naphtho[2,1-b]furan-2-on;1H-naphtho[2,1-b]furan-2-one;

Chemical Property of NAPHTHO[2,1-B]FURAN-2(1H)-ONE

Chemical Property:

• Vapor Pressure: 1.48E-05mmHg at 25°C
• Melting Point: 104-106oC
• Boiling Point: 366.2°Cat760mmHg
• Flash Point: 153.3°C
• PSA: 26.30000
• Density: 1.313g/cm³
• LogP: 2.30130

Purity/Quality:

98%Min ^*data from raw suppliers

Naphtho[2,1-B]furan-2(1H)-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of NAPHTHO[2,1-B]FURAN-2(1H)-ONE

There total 26 articles about NAPHTHO[2,1-B]FURAN-2(1H)-ONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

1,2-dihydronaphtho<2,1-b>furan-1,2-diol (133523-53-2) → 1H-naphtho[2,1-b]furan-2-one (4352-63-0)

Guidance literature:

With hydrogenchloride; In chloroform; at 50 ℃; for 1h;

DOI:10.1021/jo00010a029

Reference yield: 85.0%

N,N-Diethyl-2-(2-hydroxy-naphthalen-1-yl)-acetamide → 1H-naphtho[2,1-b]furan-2-one (4352-63-0)

Guidance literature:

With acetic acid; for 20h; Heating;

DOI:10.1055/s-1997-5743

Reference yield: 73.0%

(2-naphthoyl)oxyacetic acid (120-23-0) → 1H-naphtho[2,1-b]furan-2-one (4352-63-0) + β-naphthol (135-19-3) + 2-hydroxynaphthalene-1-carbaldehyde (708-06-5)

Guidance literature:

With air; In water; for 7h; Product distribution; Ambient temperature; Irradiation; also under argon atmoshere; photodegradation pathways;

DOI:10.1021/jf960699l

upstream raw materials:

2-(2-hydroxynaphthalen-1-yl)acetic acid

(2-methoxy-[1]naphthyl)-acetic acid

chloroacetic acid

β-naphthol

Refernces

• 1、 Clement,Shieh. "-". . p. 1850. Retrieved 1960.
• 2、 Graf, Katharina,Ruehl, Carmen L.,Rudolph, Matthias,Rominger, Frank,Hashmi, A. Stephen K.. "Metal-free oxidative cyclization of alkynyl aryl ethers to benzofuranones". supporting information. p. 12727 - 12731. Retrieved 2013/12/04.