N-Dodecylacrylamide

Base Information

• Chemical Name: N-Dodecylacrylamide
• CAS No.: 1506-53-2
• Molecular Formula: C15H29NO
• Molecular Weight: 239.401
• Hs Code.: 2924199090
• European Community (EC) Number: 216-136-0
• DSSTox Substance ID: DTXSID50164580
• Nikkaji Number: J107.691D
• Wikidata: Q83033639
• Mol file: 1506-53-2.mol

Synonyms:N-Dodecylacrylamide;1506-53-2;N-dodecylprop-2-enamide;EINECS 216-136-0;MFCD08276361;2-Propenamide, N-dodecyl-;SCHEMBL232770;N-Dodecylacrylamide, >/=97%;DTXSID50164580;BAA50653;AS-58480;SY054129;CS-0167914;D3316;D90172;A884147

Chemical Property of N-Dodecylacrylamide

Chemical Property:

• Vapor Pressure: 8.41E-06mmHg at 25°C
• Melting Point: 58 °C
• Refractive Index: 1.452
• Boiling Point: 374.34 °C at 760 mmHg
• PKA: 15.03±0.46(Predicted)
• Flash Point: 229.74 °C
• PSA: 32.59000
• Density: 0.864 g/cm³
• LogP: 5.04980
• XLogP3: 5.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 12
• Exact Mass: 239.224914549
• Heavy Atom Count: 17
• Complexity: 189

Purity/Quality:

99% ^*data from raw suppliers

N-Dodecylacrylamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCNC(=O)C=C

Technology Process of N-Dodecylacrylamide

There total 10 articles about N-Dodecylacrylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.6%

C19H40N2O → N-dodecanoylacrylamide (1506-53-2)

Guidance literature:

With tetrabutylammomium bromide; p-benzoquinone; In toluene;

Reference yield: 83.4%

n-Dodecylamine (124-22-1) + acryloyl chloride (814-68-6,25189-84-8) → N-dodecanoylacrylamide (1506-53-2)

Guidance literature:

With triethylamine; In monoethylene glycol diethyl ether; water; at 20 - 40 ℃; for 2h; Inert atmosphere;

Reference yield: 72.0%

n-Dodecylamine (124-22-1) + (3-methoxypropyl)amide (15438-67-2) → N-dodecanoylacrylamide (1506-53-2)

Guidance literature:

With sodium hydroxide;

upstream raw materials:

n-Dodecylamine

acrylic acid methyl ester

acrylic acid

acryloyl chloride

Downstream raw materials:

4-nitrobenzyl chloride

4-nitro-benzoic acid

1-benzylaziridine-2-(N-n-dodecyl)carboxamide

1-(p-methoxybenzyl)aziridine-2-(N-n-dodecyl)carboxamide

Refernces

• 1、 -. "Synthesis and refining method of N-alkyl acrylamide". Paragraph 0037; 0038. . Retrieved 2018/09/08.
• 2、 -. "Synthesis of sialic-acid-group-containing lipid derivatives and application of sialic-acid-group-containing lipid derivatives in pharmaceutical preparations". Paragraph 0131; 0132; 0133. . Retrieved 2017/06/28.