Aminooxyacetic acid

Base Information

• Chemical Name: Aminooxyacetic acid
• CAS No.: 645-88-5
• Molecular Formula: C2H5 N O3
• Molecular Weight: 91.0666
• UNII: 14I68GI3OQ
• DSSTox Substance ID: DTXSID50214756
• Nikkaji Number: J36.275A
• Wikipedia: Aminooxyacetic_acid
• Wikidata: Q4746466
• Pharos Ligand ID: BKPT6SW1ZUBP
• Metabolomics Workbench ID: 146688
• ChEMBL ID: CHEMBL347862
• Mol file: 645-88-5.mol

Synonyms:Acid, Aminooxyacetic;Aminooxyacetate;Aminooxyacetic Acid;Carboxymethoxyamine

Chemical Property of Aminooxyacetic acid

Chemical Property:

• Melting Point: 138℃
• Refractive Index: 1.4264 (estimate)
• Boiling Point: 327℃
• PKA: 1.92±0.10(Predicted)
• Flash Point: 151℃
• PSA: 75.38000
• Density: 1.375
• LogP: -1.67310
• XLogP3: -3.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 91.026943022
• Heavy Atom Count: 6
• Complexity: 52.8

Purity/Quality:

99%, ^*data from raw suppliers

Aminooxy-aceticacid 97% ^*data from reagent suppliers

Safty Information:

• Safety Statements: Poison by subcutaneous and intraperitoneal routes. Mutation data reported. When heated to decomposition it e"> x." target="_blank">Poison by subcutaneous and intraperitoneal routes. Mutation data reported. When heated to decomposition it e

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C(C(=O)O)ON

Technology Process of Aminooxyacetic acid

There total 14 articles about Aminooxyacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

N-(ethoxy carbonyl methoxy)-phthalimide (5251-81-0) → aminooxyacetic acid (645-88-5)

Guidance literature:

With hydrogenchloride; In water; at 75 ℃; for 4h; Reagent/catalyst;

Reference yield:

O-methoxycarbonylmethylhydroxylamine (25184-48-9) → aminooxyacetic acid (645-88-5)

Guidance literature:

O-methoxycarbonylmethylhydroxylamine; With water; sodium hydroxide; In methanol; at 70 ℃; for 2h;

With hydrogenchloride; In water; pH=1;

Reference yield:

2-(aminooxy)acetic acid hemihydrochloride → aminooxyacetic acid (645-88-5)

Guidance literature:

With sodium carbonate; In water; pH=5;

upstream raw materials:

ethyl N-(ethoxycarbonyl)aminooxyacetate

Benzylidenaminooxy-essigsaeure

N-benzoylaminooxyacetic acid

chloroacetic acid

Downstream raw materials:

benzaldehyde imino-oxy acetic acid

(1-phenyl-ethylidenaminooxy)-acetic acid

[(propan-2-ylideneamino)oxy]acetic acid

{[((E)-4-phenylbut-3-en-2-ylidene)amino]oxy}acetic acid

Refernces

• 1、 -. "INHIBITORS OF THE NOTCH SIGNALLING PATHWAY AND SECRETION FOR USE IN MEDICINE". Page/Page column 44. . Retrieved 2014/01/07.
• 2、 -. "Monobactam hydrazide derivatives". . . Retrieved 2008/06/13.