Benzamide, 3-chloro-5-ethyl-6-hydroxy-2-methoxy-N-((1-methyl-2-pyrrolidinyl)methyl)-, monohydrochloride, (S)-

Base Information

• Chemical Name: Benzamide, 3-chloro-5-ethyl-6-hydroxy-2-methoxy-N-((1-methyl-2-pyrrolidinyl)methyl)-, monohydrochloride, (S)-
• CAS No.: 101536-80-5
• Molecular Formula: C16H23 Cl N2 O3 . Cl H
• Molecular Weight: 363.32
• DSSTox Substance ID: DTXSID00143986
• Mol file: 101536-80-5.mol

Synonyms:FLB 524 hydrochloride;Benzamide, 3-chloro-5-ethyl-6-hydroxy-2-methoxy-N-((1-methyl-2-pyrrolidinyl)methyl)-, monohydrochloride, (S)-;S-(-)-3-Chloro-5-ethyl-6-hydroxy-N-((1-methyl-2-pyrrolidinyl)methyl)-o-anisamide HCl;S-(-)-5-Chloro-3-ethyl-6-methoxy-N-((1-methyl-2-pyrrolidinyl)methyl)salicylamide HCl;101536-80-5;DTXSID00143986;LS-26088

Chemical Property of Benzamide, 3-chloro-5-ethyl-6-hydroxy-2-methoxy-N-((1-methyl-2-pyrrolidinyl)methyl)-, monohydrochloride, (S)-

Chemical Property:

• Vapor Pressure: 1.46E-07mmHg at 25°C
• Boiling Point: 417.4°Cat760mmHg
• Flash Point: 206.2°C
• Density: g/cm³
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 362.1163980
• Heavy Atom Count: 23
• Complexity: 382

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC1=CC(=C(C(=C1O)C(=O)NCC2CCCN2C)OC)Cl.Cl
• Isomeric SMILES: CCC1=CC(=C(C(=C1O)C(=O)NC[C@@H]2CCCN2C)OC)Cl.Cl

Technology Process of Benzamide, 3-chloro-5-ethyl-6-hydroxy-2-methoxy-N-((1-methyl-2-pyrrolidinyl)methyl)-, monohydrochloride, (S)-

There total 1 articles about Benzamide, 3-chloro-5-ethyl-6-hydroxy-2-methoxy-N-((1-methyl-2-pyrrolidinyl)methyl)-, monohydrochloride, (S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

(S)-(+)-5-chloro-3-ethyl-6-methoxy-N-(2-pyrrolidinylmethyl)salicylamide (97849-49-5) + methyl iodide (74-88-4) → s(-)-5-chloro-3-ethyl-6-methoxy-N-<(1-methyl-2-pyrrolidinyl)methyl>salicylamide hydrochloride (101536-80-5)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 35 ℃; for 0.25h;

upstream raw materials:

(S)-(+)-5-chloro-3-ethyl-6-methoxy-N-(2-pyrrolidinylmethyl)salicylamide

methyl iodide

Refernces