Decanoic acid, 2-hydroxy-, (2R)-

Base Information

• Chemical Name: Decanoic acid, 2-hydroxy-, (2R)-
• CAS No.: 70267-24-2
• Molecular Formula: C10H20O3
• Molecular Weight: 188.267
• Mol file: 70267-24-2.mol

Synonyms:

Chemical Property of Decanoic acid, 2-hydroxy-, (2R)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Decanoic acid, 2-hydroxy-, (2R)-

There total 11 articles about Decanoic acid, 2-hydroxy-, (2R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-decanoic acid (334-48-5) → nonan-1-al (124-19-6) + (R)-2-hydroxydecanoic acid (70267-24-2,37639-46-6)

Guidance literature:

With phosphate buffer pH 6.0; oxygen; Triton X-100; In water; for 6h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; extract of young pea leaves (Pisum sativum);

DOI:10.1016/0957-4166(96)00283-2

Reference yield:

DL-2-hydroxydecanoic acid (5393-81-7,37639-46-6) → 2-oxodecanoic acid (333-60-8) + (R)-2-hydroxydecanoic acid (70267-24-2,37639-46-6)

Guidance literature:

With glycolate oxidase from Spinacia oleracea; oxygen; ethylenediamine; Flavin mononucleotide; In water; for 22h;

DOI:10.1021/jo971298n

Reference yield:

DL-2-hydroxydecanoic acid (5393-81-7,37639-46-6) → (R)-2-hydroxydecanoic acid (70267-24-2,37639-46-6)

Guidance literature:

Yield given;

DOI:10.1016/S0957-4166(00)80509-1

upstream raw materials:

L-2-aminodecanoic acid

DL-2-hydroxydecanoic acid

D-2-aminodecanoic acid

1-decanoic acid

Downstream raw materials:

(R)-1-O-Benzyl-1,2-decandiol

Refernces

• 1、 Xu, Jian,Hu, Yujing,Fan, Jiajie,Arkin, Mamatjan,Li, Danyang,Peng, Yongzhen,Xu, Weihua,Lin, Xianfu,Wu, Qi. "Light-Driven Kinetic Resolution of α-Functionalized Carboxylic Acids Enabled by an Engineered Fatty Acid Photodecarboxylase". supporting information. p. 8474 - 8478. Retrieved 2019/05/24.
• 2、 Adam, Waldemar,Lazarus, Michael,Boss, Barbara,Saha-Moeller, Chantu R.,Humpf, Hans-Ulrich,Schreier, Peter. "Enzymatic Resolution of Chiral 2-Hydroxy Carboxylic Acids by Enantioselective Oxidation with Molecular Oxygen Catalyzed by the Glycolate Oxidase from Spinach (Spinacia oleracea)". . p. 7841 - 7843. Retrieved 2007/10/03.