Diisovalerylmethane

Base Information

• Chemical Name: Diisovalerylmethane
• CAS No.: 7307-08-6
• Molecular Formula: C11H20O2
• Molecular Weight: 184.279
• Hs Code.: 2914199090
• Mol file: 7307-08-6.mol

Synonyms:2,8-dimethyl-nonane-4,6-dione;2,8-Dimethyl-nonan-4,6-dion;4,6-Nonanedione,2,8-dimethyl;diisobutyrylmethane;2,8-Dimethyl-4,6-nonanedione;diisovalerylmethane;

Chemical Property of Diisovalerylmethane

Chemical Property:

• Refractive Index: 1.4555 (589.3 nm 20℃)
• Boiling Point: 115-116℃ (20 Torr)
• PKA: 9.50±0.10(Predicted)
• PSA: 34.14000
• Density: 0.9054 g/cm3
• LogP: 2.60690
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C

Purity/Quality:

98%, ^*data from raw suppliers

2,8-Dimethylnonane-4,6-dione ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Diisovalerylmethane

There total 8 articles about Diisovalerylmethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

Ethyl isovalerate (108-64-5) + 4-methyl-2-pentanone (108-10-1) → 2,8-dimethylnonane-4,6-dione (7307-08-6)

Guidance literature:

With potassium tert-butylate; In N,N-dimethyl-formamide; at 50 ℃; Inert atmosphere;

DOI:10.1021/acs.orglett.0c01057

Reference yield: 55.0%

6-hydroxy-2,8-dimethyl-4-nonanone (107977-25-3) → 2,8-dimethylnonane-4,6-dione (7307-08-6)

Guidance literature:

With jones reagent; In acetone; at 0 ℃;

DOI:10.1021/jo000781m

Reference yield: 43.0%

methyl 3-methylbutanoate (556-24-1) + 4-methyl-2-pentanone (108-10-1) → 2,8-dimethylnonane-4,6-dione (7307-08-6)

Guidance literature:

With potassium tert-butylate; In N,N-dimethyl-formamide; at 50 ℃; Inert atmosphere;

upstream raw materials:

3-methylbutyric acid

Ethyl isovalerate

4-methyl-2-pentanone

2,8-dimethyl-nonane-4,6-dione enol tautomer

Refernces

• 1、 -. "ORGANOMETALLIC COMPLEX, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE". Paragraph 0188; 0190; 0191. . Retrieved 2018/06/15.
• 2、 Nandurkar, Nitin S.,Bhanushali, Mayur J.,Patil, Dinkar S.,Bhanage, Bhalchandra M.. "Synthesis of sterically hindered 1,3-diketones". . p. 4111 - 4115. Retrieved 2008/03/13.