1-deoxy-2,5-O-methylidenehexitol

Base Information

• Chemical Name: 1-deoxy-2,5-O-methylidenehexitol
• CAS No.: 5399-33-7
• Molecular Formula: C₇H₁₄O₅
• Molecular Weight: 178.185
• Mol file: 5399-33-7.mol

Synonyms:

Chemical Property of 1-deoxy-2,5-O-methylidenehexitol

Chemical Property:

• Vapor Pressure: 1.6E-06mmHg at 25°C
• Boiling Point: 356.8°Cat760mmHg
• Flash Point: 169.6°C
• Density: 1.283g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-deoxy-2,5-O-methylidenehexitol

There total 11 articles about 1-deoxy-2,5-O-methylidenehexitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-iodo-O2,O5-methanediyl-1-deoxy-D-mannitol (910884-54-7) → O2,O5-methanediyl-1-deoxy-D-mannitol (5399-33-7)

Guidance literature:

With methanol; nickel; barium methoxide;

DOI:10.1021/ja01226a055

Reference yield:

O4-acetoxymethyl-O3,O6-diacetyl-O2,O5-methanediyl-1-deoxy-L-mannitol (55645-93-7) → O2,O5-methanediyl-1-deoxy-L-mannitol (5399-33-7)

Guidance literature:

With methanol; barium methoxide;

DOI:10.1021/ja01226a055

Reference yield:

L-rhamnitol (488-28-8) → O2,O5-methanediyl-1-deoxy-L-mannitol (5399-33-7)

Guidance literature:

Multi-step reaction with 3 steps

1: aqueous hydrochloric acid

2: acetic acid; sulfuric acid

3: barium methylate; methanol

With hydrogenchloride; methanol; sulfuric acid; barium methoxide; acetic acid;

DOI:10.1021/ja01226a055

upstream raw materials:

O⁴-acetoxymethyl-O³,O⁶-diacetyl-O²,O⁵-methanediyl-1-deoxy-L-mannitol

L-rhamnitol

O²,O⁵;O⁴,O⁶-dimethanediyl-1-deoxy-L-mannitol

1-iodo-O²,O⁵-methanediyl-1-deoxy-D-mannitol

Downstream raw materials:

O³,O⁴,O⁶-triacetyl-O²,O⁵-methanediyl-1-deoxy-L-mannitol

O²,O⁵-methanediyl-O⁶-(toluene-4-sulfonyl)-1-deoxy-L-mannitol

O²,O⁵-methanediyl-O³,O⁴,O⁶-tris-(toluene-4-sulfonyl)-1-deoxy-L-mannitol

1-iodo-O²,O⁵-methanediyl-O³,O⁴-bis-(toluene-4-sulfonyl)-1,6-dideoxy-L-mannitol