Oleamidopropyl dimethylamine

Base Information

• Chemical Name: Oleamidopropyl dimethylamine
• CAS No.: 109-28-4
• Deprecated CAS: 3271-67-8
• Molecular Formula: C23H46N2O
• Molecular Weight: 366.631
• Hs Code.: 2924199090
• European Community (EC) Number: 203-661-5
• NSC Number: 258347
• UNII: 79K39JU7RN
• DSSTox Substance ID: DTXSID10873803
• Nikkaji Number: J193.576C
• Wikidata: Q27266762
• Mol file: 109-28-4.mol

Synonyms:Lexamine O-13;N-(3-(dimethylamino)propyl)oleamide;oleamidopropyl dimethylamine;Tegamine 0-13

Chemical Property of Oleamidopropyl dimethylamine

Chemical Property:

• Vapor Pressure: 2.57E-10mmHg at 25°C
• Refractive Index: 1.471
• Boiling Point: 504.8 °C at 760 mmHg
• Flash Point: 259.1 °C
• PSA: 32.34000
• Density: 0.883 g/cm³
• LogP: 6.48270
• Water Solubility.: 1.26g/L at 20℃
• XLogP3: 7.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 19
• Exact Mass: 366.361014095
• Heavy Atom Count: 26
• Complexity: 326

Purity/Quality:

99.9% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCC=CCCCCCCCC(=O)NCCCN(C)C
• Isomeric SMILES: CCCCCCCC/C=C\CCCCCCCC(=O)NCCCN(C)C
• Uses: Oleamidopropyl dimethylamine is a cationic emulsifier in cosmetics, such as body lotions, creams, shampoos, hair rinse preparations, etc.

Technology Process of Oleamidopropyl dimethylamine

There total 3 articles about Oleamidopropyl dimethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

cis-Octadecenoic acid (112-80-1,2027-47-6) + 1-amino-3-(dimethylamino)propane (109-55-7) → (9Z)-N-[3-(dimethylamino)propyl]octadec-9-enamide (109-28-4)

Guidance literature:

With K/γ-Al₂ O₃; at 40 - 120 ℃; for 11h;

Reference yield: 95.0%

Methyl oleate (112-62-9) + 1-amino-3-(dimethylamino)propane (109-55-7) → (9Z)-N-[3-(dimethylamino)propyl]octadec-9-enamide (109-28-4)

Guidance literature:

With zeolite; at 115 - 120 ℃; for 12h; Dean-Stark;

DOI:10.1134/S1070427217070126

Reference yield:

→ (9Z)-N-[3-(dimethylamino)propyl]octadec-9-enamide (109-28-4)

Guidance literature:

entspr. Saeurechlorid, Dimethylaminopropylamin;

upstream raw materials:

cis-Octadecenoic acid

1-amino-3-(dimethylamino)propane

Methyl oleate

Downstream raw materials:

(Z)-N,N-dimethyl-3-(octadec-9-enamido) propan-1-amine oxide

oleamidopropyl betaine

Refernces

• 1、 Feng, Dan,Zhang, Yongmin,Chen, Quansheng,Wang, Jiyu,Li, Bin,Feng, Yujun. "Synthesis and surface activities of amidobetaine surfactants with ultra-long unsaturated hydrophobic chains". . p. 657 - 661. Retrieved 2012.
• 2、 Hussain, S. M. Shakil,Kamal, Muhammad Shahzad,El Ali, Bassam,Sultan, Abdullah S.. "Synthesis and Evaluation of Novel Amido-Amine Cationic Gemini Surfactants Containing Flexible and Rigid Spacers". . p. 777 - 788. Retrieved 2017.
• 3、 Hussain, S. M. Shakil,Kamal, Muhammad Shahzad,Mahboob, Ahmad. "Synthesis and evaluation of magnetic surfactants for high temperature oilfield application". . . Retrieved 2021/08/25.
• 4、 Shakil Hussain,Kamal, Muhammad Shahzad. "Effect of large spacer on surface activity, thermal, and rheological properties of novel amido-amine cationic gemini surfactants". . p. 1131 - 1137. Retrieved 2017/08/08.