2-Chloro-1-(3,4-difluorophenyl)ethanone

Base Information Edit

Chemical Name:2-Chloro-1-(3,4-difluorophenyl)ethanone
CAS No.:51336-95-9
Molecular Formula:C8H5ClF2O
Molecular Weight:190.577
Hs Code.:2914700090
European Community (EC) Number:610-651-8
DSSTox Substance ID:DTXSID40368434
Nikkaji Number:J1.376.121C
Wikidata:Q72518400
Mol file:51336-95-9.mol

Synonyms:51336-95-9;2-chloro-1-(3,4-difluorophenyl)ethanone;2-Chloro-1-(3,4-difluoro-phenyl)-ethanone;2-Chloro-3',4'-difluoroacetophenone;2-chloro-1-(3,4-difluorophenyl)ethan-1-one;a-Chloro-3,4-difluoroacetophenone;MFCD03966888;2-Chloro-1-(3,4-difluoro-phenyl)ethanone;Ethanone, 2-chloro-1-(3,4-difluorophenyl)-;EC 610-651-8;2-CHLORO-3,4-DIFLUOROACETOPHENONE;3,4-DIFLUOROPHENACYL CHLORIDE;SCHEMBL247898;DTXSID40368434;VMEDAWUIKFAFJQ-UHFFFAOYSA-N;BCP30757;CL8638;AKOS000115684;AC-3612;alpha-Chloro-3',4'-difluoroacetophenone;AS-19970;SY018239;2-chloro-1-(3,4-difluorophenyl) ethanone;A7575;AM20040597;BB 0253894;C3215;CS-0011365;FT-0650897;EN300-01950;Z56891298;2-Chloro-3 inverted exclamation mark ,4 inverted exclamation mark -difluoroacetophenone;2-Chloro-3',4'-difluoroacetophenone pound>>2-chloro-1-(3,4-difluorophenyl)ethan-1-one

Suppliers and Price of 2-Chloro-1-(3,4-difluorophenyl)ethanone

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Chloro-1-(3,4-difluoro-phenyl)-ethanone
1g
$ 75.00

TCI Chemical
2-Chloro-3',4'-difluoroacetophenone >98.0%(GC)
5g
$ 90.00

TCI Chemical
2-Chloro-3',4'-difluoroacetophenone >98.0%(GC)
1g
$ 30.00

SynQuest Laboratories
3,4-Difluorophenacyl chloride
5 g
$ 34.00

SynQuest Laboratories
3,4-Difluorophenacyl chloride
1 g
$ 16.00

SynQuest Laboratories
3,4-Difluorophenacyl chloride
25 g
$ 90.00

Chemenu
2-chloro-1-(3,4-difluorophenyl)ethanone 95+%
1000g
$ 1288.00

BLDpharm
2-Chloro-1-(3,4-difluorophenyl)ethanone 98+%
25g
$ 57.00

BLDpharm
2-Chloro-1-(3,4-difluorophenyl)ethanone 98+%
5g
$ 22.00

Azepine
2-Chloro-3',4'-difluoroacetophenone 98
25 g
$ 190.00

Total 104 raw suppliers

Chemical Property of 2-Chloro-1-(3,4-difluorophenyl)ethanone Edit

Chemical Property:

Vapor Pressure:0.0155mmHg at 25°C
Refractive Index:1.495
Boiling Point:256.3 °C at 760 mmHg
Flash Point:108.8 °C
PSA：17.07000
Density:1.353 g/cm³
LogP:2.38630
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Sensitive.:Lachrymatory
Solubility.:soluble in Methanol
XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:189.9996988
Heavy Atom Count:12
Complexity:174

Purity/Quality:

99% ^*data from raw suppliers

2-Chloro-1-(3,4-difluoro-phenyl)-ethanone ^*data from reagent suppliers

Safty Information:

Pictogram(s): C, Xi
Hazard Codes:C,Xi

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=C(C=C1C(=O)CCl)F)F
Use Description 1. **Formamide, N-[2-(azidomethyl)phenyl]-**: This compound finds applications in various fields due to its versatile reactivity. In organic synthesis, it acts as a reagent for the introduction of azide groups into molecules, which is valuable in the development of pharmaceuticals and agrochemicals. In the field of materials science, it plays a role in the fabrication of polymers, coatings, and films. Moreover, in biochemistry and molecular biology, it is utilized as a denaturant in DNA and RNA gel electrophoresis, helping to unwind double-stranded nucleic acids for analysis. Its ability to modify and crosslink molecules makes it a valuable tool in different scientific disciplines. 2. **2-Chloro-1-(3,4-difluoro-phenyl)-ethanone**: This compound serves distinct purposes in various fields. In the realm of pharmaceuticals, it can be employed as an intermediate for the synthesis of pharmaceutical compounds. In the agrochemical industry, it plays a role in the development of pesticides and herbicides due to its ability to introduce functional groups that enhance the bioactivity of these chemicals. Additionally, in the field of organic chemistry, it serves as a valuable building block for the creation of complex molecules. Its role as a synthetic intermediate underscores its significance in drug discovery, agriculture, and chemical research.

Technology Process of 2-Chloro-1-(3,4-difluorophenyl)ethanone

There total 1 articles about 2-Chloro-1-(3,4-difluorophenyl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 367-11-3
ortho-difluorobenzene

: 79-04-9
chloroacetyl chloride

: 51336-95-9
2-chloro-1-(3,4-difluorophenyl)ethan-1-one

Guidance literature:: chloroacetyl chloride; With aluminum (III) chloride; In dichloromethane; for 0.666667h; Inert atmosphere; Reflux;

ortho-difluorobenzene; In dichloromethane; for 3h; Reflux;

Reference yield: 98.9%

: 51336-95-9
2-chloro-1-(3,4-difluorophenyl)ethan-1-one

: 1006376-60-8
(1S)-2-chloro-1-(3,4-difluorophenyl)-1-ethanol

Guidance literature:: With sodium tetrahydroborate; (S)-diphenylprolinol; N,N-diethylaniline hydrochloride; In 1,2-dimethoxyethane; chloroform; at 0 - 30 ℃; for 2h; Solvent;