Medica 16

Base Information

• Chemical Name: Medica 16
• CAS No.: 87272-20-6
• Molecular Formula: C20H38O4
• Molecular Weight: 342.519
• Hs Code.: 2917190090
• UNII: TC257FLPCK
• DSSTox Substance ID: DTXSID00236246
• Nikkaji Number: J525.373J
• Wikidata: Q27084045
• Pharos Ligand ID: 5W59CB7B1TN8
• ChEMBL ID: CHEMBL63829
• Mol file: 87272-20-6.mol

Synonyms:3,3,14,14-tetramethylhexanedecanedioic acid;MEDIC-16;MEDICA 16

Chemical Property of Medica 16

Chemical Property:

• Appearance/Colour: white solid
• Vapor Pressure: 8.97E-11mmHg at 25°C
• Melting Point: 154-159 °C
• Refractive Index: 1.473
• Boiling Point: 485.9 °C at 760 mmHg
• PKA: 4.51±0.10(Predicted)
• Flash Point: 261.8 °C
• PSA: 74.60000
• Density: 0.984 g/cm³
• LogP: 5.88920
• Storage Temp.: −20°C
• Solubility.: DMSO: 28 mg/mL
• XLogP3: 7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 15
• Exact Mass: 342.27700969
• Heavy Atom Count: 24
• Complexity: 336

Purity/Quality:

≥98% by HPLC ^*data from raw suppliers

MEDICA 16 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(CCCCCCCCCCC(C)(C)CC(=O)O)CC(=O)O
• Description: MEDICA 16 is a β,β''-dimethyl hexadecanedioic acid which exhibits hypolipidemic and antidiabetogenic effects in the rat. In animals that were fed a diet which was 0.25% MEDICA 16 by weight, the hypolipidemic effect consisted of a 70-80% decrease in plasma chylomicrons and VLDL-triacylglycerols as well as a 40-60% decrease in plasma VLDL-cholestrol.
• Uses: MEDICA 16 is a β,β'-dimethyl hexadecanedioic acid which exhibits hypolipidemic and antidiabetogenic effects in the rat. In animals that were fed a diet which was 0.25% MEDICA 16 by weight, the hypolipidemic effect consisted of a 70-80% decrease in plasma chylomicrons and VLDL-triacylglycerols as well as a 40-60% decrease in plasma VLDL-cholestrol. MEDICA 16 is a malic enzyme and mitochondrial glycerol-3-phosphate dehydrogenase inducer.

Technology Process of Medica 16

There total 2 articles about Medica 16 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C22H38O8 (87272-21-7) → Medica 16 (87272-20-6)

Guidance literature:

at 190 ℃; for 1h;

Reference yield:

→ Medica 16 (87272-20-6)

Guidance literature:

upstream raw materials:

C₂₂H₃₈O₈

Refernces

• 1、 -. "Long-chain α,ω-di-carboxylic acids and derivatives thereof and pharmaceutical compositions containing them". . . Retrieved 2008/06/13.