1,2-Ethanediol, 1,2-bis(4-hydroxy-3-methoxyphenyl)-

Base Information

• Chemical Name: 1,2-Ethanediol, 1,2-bis(4-hydroxy-3-methoxyphenyl)-
• CAS No.: 4464-75-9
• Molecular Formula: C₁₆H₁₈O₆
• Molecular Weight: 306.315
• DSSTox Substance ID: DTXSID10963253
• Nikkaji Number: J53.954F
• Mol file: 4464-75-9.mol

Synonyms:Hydrovanilloin;4464-75-9;1,2-Ethanediol, 1,2-bis(4-hydroxy-3-methoxyphenyl)-;1,2-bis(4-hydroxy-3-methoxyphenyl)ethane-1,2-diol;4,4'-Dihydroxy-3,3'-dimethoxyhydrobenzoin;1,2-Bis(3-methoxy-4-hydroxyphenyl)-1,2-ethanediol;Phenol, p,p'-(1,2-dihydroxyethylene)bis(o-methoxy-;SCHEMBL7901872;DTXSID10963253;O6C16H18;O6-C16-H18;LS-65527;1,2-bis-(4-hydroxy-3-methoxy-phenyl)-ethane-1,2-diol

Chemical Property of 1,2-Ethanediol, 1,2-bis(4-hydroxy-3-methoxyphenyl)-

Chemical Property:

• Vapor Pressure: 3.72E-12mmHg at 25°C
• Boiling Point: 532.2°Cat760mmHg
• Flash Point: 275.7°C
• PSA: 99.38000
• Density: 1.365g/cm³
• LogP: 1.88200
• XLogP3: 1.1
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 5
• Exact Mass: 306.11033829
• Heavy Atom Count: 22
• Complexity: 307

Purity/Quality:

99%, ^*data from raw suppliers

HYDROVANILLOIN 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=C(C=CC(=C1)C(C(C2=CC(=C(C=C2)O)OC)O)O)O

Technology Process of 1,2-Ethanediol, 1,2-bis(4-hydroxy-3-methoxyphenyl)-

There total 14 articles about 1,2-Ethanediol, 1,2-bis(4-hydroxy-3-methoxyphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

vanillin (121-33-5,8014-42-4) → 1,2-bis-(4-hydroxy-3-methoxyphenyl)ethane-1,2-diol (4464-75-9,5629-45-8)

Guidance literature:

vanillin; Electrochemical reaction;

With hydrogenchloride; In water;

DOI:10.1039/c2gc35645g

Reference yield: 85.0%

C30H30O6 → hydrovanilloin (4464-75-9,5629-45-8)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol; ethyl acetate; at 20 ℃; for 24h;

Reference yield: 69.0%

vanillin (121-33-5,8014-42-4) → hydrovanilloin (4464-75-9,5629-45-8)

Guidance literature:

With sodium hydroxide; In water; for 5h; Electrochemical reaction;

DOI:10.1039/c4gc01825g

upstream raw materials:

ethanol

vanillin

water

benzaldehyde

Downstream raw materials:

(E)-3,3'-dimethoxy-4,4'-dihydroxystilbene

1,2-Bis-(3-formyl-4,5-dimethoxy-phenyl)-ethan

1,2-Bis-(3-formyl-4-hydroxy-5-methoxy-phenyl)-ethan

1,2-Bis-(4-acetoxy-3-allyl-5-methoxyphenyl)-ethan

Refernces

• 1、 -. "NOVEL 1,2-DIPHENYLETHYLENE GLYCOL COMPOUNDS FOR COMBATING AGING OF THE SKIN, AND COSMETIC USE THEREOF". . . Retrieved 2016/07/05.
• 2、 Amarasekara, Ananda S.,Wiredu, Bernard,Razzaq, Ashfaqur. "Vanillin based polymers: I. An electrochemical route to polyvanillin". supporting information. p. 2395 - 2397. Retrieved 2013/02/22.