1-phenyl-3-(2-naphthyl)-2-pyrazoline

Base Information

• Chemical Name: 1-phenyl-3-(2-naphthyl)-2-pyrazoline
• CAS No.: 3314-37-2
• Molecular Formula: C19H16 N2
• Molecular Weight: 272.349
• Hs Code.: 2933199090
• Mol file: 3314-37-2.mol

Synonyms:2-Pyrazoline,3-(2-naphthyl)-1-phenyl- (7CI,8CI)

Chemical Property of 1-phenyl-3-(2-naphthyl)-2-pyrazoline

Chemical Property:

• Vapor Pressure: 4.14E-08mmHg at 25°C
• Boiling Point: 444.8°Cat760mmHg
• Flash Point: 222.8°C
• PSA: 15.60000
• Density: 1.13g/cm³
• LogP: 3.95480

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-phenyl-3-(2-naphthyl)-2-pyrazoline

There total 4 articles about 1-phenyl-3-(2-naphthyl)-2-pyrazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

naphthalene-2-boronic acid (32316-92-0) + 3-chloro-1-phenyl-2-pyrazoline (58469-32-2) → 3-naphthalen-2-yl-1-phenyl-4,5-dihydro-1H-pyrazole (3314-37-2) + N-cyanoethylaniline (1075-76-9)

Guidance literature:

With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In acetonitrile; at 140 ℃; for 0.0833333h; Further Variations:; Catalysts; Temperatures; Product distribution; microwave irradiation;

DOI:10.1016/j.tetlet.2005.02.075

Reference yield:

naphthalene (91-20-3,71998-51-1,72931-45-4) → 3-naphthalen-2-yl-1-phenyl-4,5-dihydro-1H-pyrazole (3314-37-2)

Guidance literature:

Multi-step reaction with 2 steps

1: AlCl₃; carbon disulfide

2: ethanol

With carbon disulfide; aluminium trichloride; ethanol;

Reference yield:

3-chloro-1-(naphthalen-2-yl)propan-1-one (22422-70-4) + phenylhydrazine (100-63-0) → 3-naphthalen-2-yl-1-phenyl-4,5-dihydro-1H-pyrazole (3314-37-2)

Guidance literature:

With ethanol;

upstream raw materials:

3-chloro-1-(naphthalen-2-yl)propan-1-one

phenylhydrazine

naphthalene-2-boronic acid

3-chloro-1-phenyl-2-pyrazoline

Refernces