Thiosemicarbazide hydrochloride

Base Information

• Chemical Name: Thiosemicarbazide hydrochloride
• CAS No.: 4346-94-5
• Molecular Formula: CH5N3S^.HCl
• Molecular Weight: 127.598
• Hs Code.: 2930909090
• European Community (EC) Number: 678-497-4
• NSC Number: 191943
• UNII: UHX25R8M22
• DSSTox Substance ID: DTXSID50195859
• Mol file: 4346-94-5.mol

Synonyms:N-aminothiourea;thiocarbamylhydrazine;thiosemicarbazide;thiosemicarbazide hydrochloride;thiosemicarbazide monohydrochloride

Chemical Property of Thiosemicarbazide hydrochloride

Chemical Property:

• Melting Point: 190-191 °C (decomp)
• Boiling Point: 208.6 °C at 760 mmHg
• Flash Point: 80 °C
• PSA: 96.16000
• Density: 1.376g/cm³
• LogP: 1.28680
• Water Solubility.: Soluble in water
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 126.9970961
• Heavy Atom Count: 6
• Complexity: 42.2

Purity/Quality:

98%,99%, ^*data from raw suppliers

Thiosemicarbazide hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C(=S)(N)NN.Cl

Technology Process of Thiosemicarbazide hydrochloride

There total 1 articles about Thiosemicarbazide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

thiosemicarbazide (79-19-6) → thiosemicarbazide hydrochloride (4346-94-5)

Guidance literature:

With hydrogenchloride; In ethanol; water;

Reference yield: 100.0%

thiosemicarbazide hydrochloride (4346-94-5) + (3-oxo-3-phenylpropyl)carbamic acid tert-butyl ester (333387-97-6) → C15H22N4O2S*ClH

Guidance literature:

In methanol; at 20 ℃; for 8h;

Reference yield: 98.0%

1-[dimethoxyphosphoryl-(3,5-di-tert-butyl-4-hydroxyphenyl)]-5-butyl-H-indole-2,3-dione + thiosemicarbazide hydrochloride (4346-94-5) → thiosemicarbazone 1-[dimethoxyphosphoryl-(3,5-di-tertbutyl-4-hydroxyphenyl)]-5-butyl-1H-indole-2,3-dione

Guidance literature:

With sodium chloride; In ethanol; water; at 70 ℃; for 3.5h;

DOI:10.1080/10426507.2016.1138308

upstream raw materials:

thiosemicarbazide

Downstream raw materials:

1-(2-hydroxy-1,2-diphenylethylidene)thiosemicarbazide

5-nitro-furfural thiosemicarbazone

4-Oxothiazolidin-2-hydrazon

5,6-bis-(2-methoxy-phenyl)-2H-[1,2,4]triazine-3-thione

Refernces

• 1、 -. "ISOFLAVONOID ANALOGS AND THEIR METAL CONJUGATES AS ANTI-CANCER AGENTS". Page/Page column 10. . Retrieved 2008/06/13.