2-((6-chloro-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl)-4-fluorobenzonitrile

Base Information Edit

Chemical Name:2-((6-chloro-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl)-4-fluorobenzonitrile
CAS No.:865759-24-6
Molecular Formula:C13H9ClFN3O2
Molecular Weight:293.685
Hs Code.:
Mol file:865759-24-6.mol

Synonyms:2-[(6-CHLORO-3,4-DIHYDRO-3-METHYL-2,4-DIOXO-1(2H)-PYRIMIDINYL)METHYL]-4-FLUOROBENZONITRILE;2-((6-chloro-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzonitrile;

Suppliers and Price of 2-((6-chloro-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl)-4-fluorobenzonitrile

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

ChemScene
Benzonitrile,2-[(6-chloro-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl)methyl]-4-fluoro-
100mg
$ 185.00

aablocks
2-((6-Chloro-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzonitrile 97%
250mg
$ 438.00

Total 50 raw suppliers

Chemical Property of 2-((6-chloro-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl)-4-fluorobenzonitrile Edit

Chemical Property:

Boiling Point:417.7±55.0 °C(Predicted)
PKA:-3.66±0.40(Predicted)
PSA：67.79000
Density:1.49±0.1 g/cm3(Predicted)
LogP:1.25948

Purity/Quality:

98%,99%, ^*data from raw suppliers

Benzonitrile,2-[(6-chloro-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl)methyl]-4-fluoro- ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-((6-chloro-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl)-4-fluorobenzonitrile

There total 8 articles about 2-((6-chloro-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl)-4-fluorobenzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.93%

: 4318-56-3
3-methyl-6-chlorouracil

: 421552-12-7
2-(bromomethyl)-4-fluorobenzonitrile

: 865759-24-6
2-[(6-chloro-3-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)methyl]-4-fluorobenzonitrile

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In 1-methyl-pyrrolidin-2-one; at 20 - 55 ℃; for 4h; Time; Temperature;

Reference yield: 88.1%

: C₁₃H₁₀FN₃O₃

: 865759-24-6
2-[(6-chloro-3-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)methyl]-4-fluorobenzonitrile

Guidance literature:: With trichlorophosphate; In water monomer; at 0 - 85 ℃; for 6h; Temperature;

Reference yield: 82.0%

: 1261742-22-6
2-(chloromethyl)-4-fluorobenzonitrile

: 4318-56-3
3-methyl-6-chlorouracil

: 865759-24-6
2-[(6-chloro-3-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)methyl]-4-fluorobenzonitrile

Guidance literature:: 3-methyl-6-chlorouracil; With N-ethyl-N,N-diisopropylamine; In 1-methyl-pyrrolidin-2-one; at 20 ℃; for 0.5h;

2-(chloromethyl)-4-fluorobenzonitrile; In 1-methyl-pyrrolidin-2-one; toluene; at 60 ℃; for 1h; Temperature; Time;