Proligestone

Base Information

• Chemical Name: Proligestone
• CAS No.: 23873-85-0
• Molecular Formula: C24H34 O4
• Molecular Weight: 386.532
• European Community (EC) Number: 245-922-6
• UNII: 55772LJ01V
• DSSTox Substance ID: DTXSID501016687
• Nikkaji Number: J15.818F
• Wikipedia: Proligestone
• Wikidata: Q907070
• NCI Thesaurus Code: C77016
• Metabolomics Workbench ID: 155826
• ChEMBL ID: CHEMBL2106696
• Mol file: 23873-85-0.mol

Synonyms:14 alpha, 17 alpha-propylidenedioxyprogesterone;14,17-dihydroxypregn-4-ene-3,20-dione cyclic acetal with propionaldehyde;Delvosteron;proligestone

Chemical Property of Proligestone

Chemical Property:

• Vapor Pressure: 9.28E-11mmHg at 25°C
• Melting Point: 93-94 °C
• Boiling Point: 517°Cat760mmHg
• Flash Point: 224.5°C
• PSA: 52.60000
• Density: 1.18g/cm³
• LogP: 4.75160
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 386.24570956
• Heavy Atom Count: 28
• Complexity: 771

Purity/Quality:

98%Min ^*data from raw suppliers

Proligestone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC1OC23CCC(C2(CCC4C3CCC5=CC(=O)CCC45C)C)(O1)C(=O)C
• Isomeric SMILES: CCC1O[C@@]23CC[C@]([C@]2(CC[C@H]4[C@H]3CCC5=CC(=O)CC[C@]45C)C)(O1)C(=O)C
• Uses: Proligestone is a derivative of 17α-Hydroxy Progesterone (H952330), which is a metabolite of Progesterone (P755900), a steroid hormone produced by the corpus luteum. Proligestone maintains the ability to affect the hypothalmic-pituitary-adrenocortical axis and glucose homeostasis. Proligestone is a derivative of 17α-Hydroxy Progesterone (H952330), which is a metabolite of Progesterone (P755900), a steroid hormone produced by the corpus luteum. Proligestone maintains the ability to affect the hypothalmic-pituitary-adrenocortical axis and glucose homeostasis.

Technology Process of Proligestone

There total 1 articles about Proligestone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ proligestone (23873-85-0)

Guidance literature:

Entspr. Dihydroxyverb., Propionaldehyd;

DOI:10.1021/jm00279a008