o-Xylylene glycol dimethyl ether

Base Information

• Chemical Name: o-Xylylene glycol dimethyl ether
• CAS No.: 5707-27-7
• Molecular Formula: C10H14 O2
• Molecular Weight: 166.22
• Nikkaji Number: J201.402E
• Mol file: 5707-27-7.mol

Synonyms:SCHEMBL648491;o-xylylene glycol dimethyl ether;SCHEMBL13313113

Chemical Property of o-Xylylene glycol dimethyl ether

Chemical Property:

• Vapor Pressure: 1.31E-15mmHg at 25°C
• Boiling Point: 626.5°Cat760mmHg
• Flash Point: 332.7°C
• PSA: 73.86000
• Density: 1.2g/cm³
• LogP: 5.73750
• XLogP3: 1.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 166.099379685
• Heavy Atom Count: 12
• Complexity: 100

Purity/Quality:

PROPYL 4-(4-ETHOXYPHENYL)-7-(4-METHOXYPHENYL)-2-METHYL-5-OXO-4,6,7,8-TETRAHYDRO-1H-QUINOLINE-3-CARBOXYLATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COCC1=CC=CC=C1COC

Technology Process of o-Xylylene glycol dimethyl ether

There total 9 articles about o-Xylylene glycol dimethyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methanol (67-56-1) + α,α'-dibromo-o-xylene (91-13-4) → 1,2-bis(methoxymethyl)benzene (5707-27-7)

Guidance literature:

With silver(II) oxide; for 0.5h; Ambient temperature; Irradiation;

DOI:10.1080/00397919308009835

Reference yield:

methanol (67-56-1) + 2-(Methoxymethyl)benzaldehyde tosylhydrazone (119367-60-1) → 1,3-dihydroisobenzofuran (496-14-0) + 2-methoxymethyltoluene (15018-12-9) + α-methoxy-α,α'-dihydrobenzocyclobutene (36101-23-2,52665-63-1) + 1,2-bis(methoxymethyl)benzene (5707-27-7)

Guidance literature:

With sodium methylate; for 2h; Yield given. Further byproducts given. Yields of byproduct given; Ambient temperature; Irradiation;

DOI:10.1021/ja00186a048

Reference yield:

diethylene glycol dimethyl ether (111-96-6) + C16H17N2O3S(1-)*Na(1+) (119391-23-0) → 1,3-dihydroisobenzofuran (496-14-0) + isochromane (493-05-0) + α-methoxy-α,α'-dihydrobenzocyclobutene (36101-23-2,52665-63-1) + 1,2-bis(methoxymethyl)benzene (5707-27-7)

Guidance literature:

for 2h; Yield given. Yields of byproduct given; Ambient temperature; Irradiation;

DOI:10.1021/ja00186a048

upstream raw materials:

sodium methylate

α,α'-dibromo-o-xylene

methanol

2-(Methoxymethyl)benzaldehyde tosylhydrazone

Downstream raw materials:

2-[(methoxymethyl)methyl]benzaldehyde

dimethyl 2-methoxymethylbenzylphosphonate

(2-methoxymethyl-phenyl)-acetic acid

2-chloromethylphenylacetic acid

Refernces

• 1、 -. "PROCESS". Page/Page column 18. . Retrieved 2008/06/13.
• 2、 Ortiz,Walls,Yuste,Barrios,Sanchez-Obregon,Pinelo. "A convenient synthesis of methyl- and isopropyl-benzyl ethers using silver(II) oxide as reagent". . p. 749 - 756. Retrieved 2007/10/02.