2,5-Thiophenedicarboxylic acid

Base Information Edit

Chemical Name:2,5-Thiophenedicarboxylic acid
CAS No.:4282-31-9
Molecular Formula:C6H4O4S
Molecular Weight:172.161
Hs Code.:29349990
European Community (EC) Number:224-284-2
NSC Number:81789
UNII:5Q8A2G9Y8A
DSSTox Substance ID:DTXSID7063392
Nikkaji Number:J205.683F
Wikidata:Q27262737
Mol file:4282-31-9.mol

Synonyms:2,5-Thiophenedicarboxylic acid;4282-31-9;THIOPHENE-2,5-DICARBOXYLIC ACID;2,5-Dicarboxythiophene;C6H4O4S;2,5-Thiophene dicarboxylic acid;MFCD00016896;UNII-5Q8A2G9Y8A;5Q8A2G9Y8A;EINECS 224-284-2;NSC 81789;NSC-81789;Maybridge4_002021;SCHEMBL70493;YSWG415;2.5-Thiophenedicarboxylic acid;2,5-thiophene-dicarboxylic acid;DTXSID7063392;thiophene-2.5-dicarboxylic acid;C6-H4-O4-S;HMS1526L19;NSC81789;BBL020160;GEO-02317;STK368409;2,5-Thiophenedicarboxylic acid, 99%;AKOS000592865;THIOPHENE-2,5-DICARBOXYLICACID;AC-4925;CS-W017616;PS-3266;SB23021;NCGC00177008-02;BP-13472;SY005216;AM20100130;FT-0610503;T2347;EN300-16996;AB01326194-02;A826012;AF-960/00468047;W-106258;Q27262737;Z56855146;F3098-3802;thiophene-2,5-dicarboxylate;Thiophene-2,5-dicarboxylic acid

Suppliers and Price of 2,5-Thiophenedicarboxylic acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,5-Dicarboxythiophene
1g
$ 45.00

TRC
2,5-Dicarboxythiophene
25g
$ 65.00

TCI Chemical
2,5-Thiophenedicarboxylic Acid >98.0%(GC)(T)
25g
$ 148.00

TCI Chemical
2,5-Thiophenedicarboxylic Acid >98.0%(GC)(T)
5g
$ 49.00

SynQuest Laboratories
Thiophene-2,5-dicarboxylic acid
50 g
$ 23.00

Sigma-Aldrich
2,5-Thiophenedicarboxylic acid 99%
25g
$ 71.00

Sigma-Aldrich
2,5-Thiophenedicarboxylic acid 99%
5g
$ 65.50

Oakwood
2,5-Thiophenedicarboxylic acid 98%
25g
$ 20.00

Matrix Scientific
Thiophene-2,5-dicarboxylic acid 97%
5g
$ 21.00

Matrix Scientific
Thiophene-2,5-dicarboxylic acid 97%
25g
$ 51.00

Total 125 raw suppliers

Chemical Property of 2,5-Thiophenedicarboxylic acid Edit

Chemical Property:

Appearance/Colour:white to light yellow crystal powder
Vapor Pressure:1.1E-08mmHg at 25°C
Melting Point:>300 °C(lit.)
Refractive Index:1.5500 (estimate)
Boiling Point:444.6 °C at 760 mmHg
PKA:2.76±0.10(Predicted)
Flash Point:222.7 °C
PSA：102.84000
Density:1.655 g/cm³
LogP:1.14450
Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature
Water Solubility.:Very soluble in water.
XLogP3:1.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:171.98302978
Heavy Atom Count:11
Complexity:171

Purity/Quality:

99% ^*data from raw suppliers

2,5-Dicarboxythiophene ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36-37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=C(SC(=C1)C(=O)O)C(=O)O
Recent ClinicalTrials:Efficacy and Safety Assessment of T2347 Versus Xalacom? in Ocular Hypertensive or Glaucomatous Patients
Uses 2,5-Thiophenedicarboxylic acid may be used as a thiophene based linker in the preparation of magnesium coordination networks. It may also be used as a precursor in the synthesis of 2,5-bis-benzoxazoyl-thiophene (EBF).It may be used in the synthesis of the following:new cobalt(II) thiophenedicarboxylate coordination polymernovel mesogenic thiophene based supramolecular liquid crystalstwo novel coordination polymers with the formula {[Ln2(2,5-tdc)3(dmso)2]H2O}n (Ln = Tb(III) and Dy(III)), (2,5-tdc2 = 2,5-thiophenedicarboxylate and dmso = dimethylsulfoxide)

Technology Process of 2,5-Thiophenedicarboxylic acid

There total 26 articles about 2,5-Thiophenedicarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 18853-40-2
2,5-thiophenedicarbonitrile

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

Guidance literature:: With hydrogenchloride; for 6h; Heating;

Reference yield: 75.58%

: 124-04-9
Adipic acid

: 4282-31-9
Thiophene-2,5-dicarboxylic acid

Guidance literature:: Adipic acid; With dmap; thionyl chloride; at 78 - 81 ℃; for 3.5h; Large scale;

With sodium hydroxide; In water; at 70 - 72 ℃; for 2h; pH=9.3 - 10; Reagent/catalyst; Temperature; pH-value; Large scale;