phenanthridine-6-carbaldehyde

Base Information

• Chemical Name: phenanthridine-6-carbaldehyde
• CAS No.: 24160-09-6
• Molecular Formula: C14H9 N O
• Molecular Weight: 207.232
• Mol file: 24160-09-6.mol

Synonyms:NSC 152138

Chemical Property of phenanthridine-6-carbaldehyde

Chemical Property:

• Vapor Pressure: 2.88E-07mmHg at 25°C
• Boiling Point: 420.2°Cat760mmHg
• Flash Point: 213.8°C
• Density: 1.274g/cm³

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of phenanthridine-6-carbaldehyde

There total 15 articles about phenanthridine-6-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

7-Oxo-5-(p-toluolsulfonyl)-6,7-dihydro-5H-dibenzazepin (24127-35-3) → 6-phenanthridinecarbaldehyde (24160-09-6)

Guidance literature:

With piperidine; for 1h; Heating;

DOI:10.1055/s-1985-34137

Reference yield: 80.0%

phenanthridine (229-87-8) + 2,2-diethoxy acetic acid (20461-86-3) → 6-phenanthridinecarbaldehyde (24160-09-6)

Guidance literature:

With ammonium peroxydisulfate; caesium carbonate; In dimethyl sulfoxide; at 20 ℃; for 24h; regioselective reaction; Inert atmosphere; Irradiation; Green chemistry;

DOI:10.1055/s-0037-1609911

Reference yield: 74.0%

6-methylphenanthridine (3955-65-5) → 6-phenanthridinecarbaldehyde (24160-09-6)

Guidance literature:

With selenium(IV) oxide; In ethyl acetate; for 10h; Heating;

upstream raw materials:

6-methylphenanthridine

7-Oxo-5-(p-toluolsulfonyl)-6,7-dihydro-5H-dibenzazepin

selenium(IV) oxide

phenanthridine-6-carboxylic acid

Downstream raw materials:

1-(Phenanthridine-6'-formyl)-4-chlorophenyl-3-thiosemicarbazone

C₂₂H₁₈N₄OS

C₁₆H₁₄N₂O₃PS^(1-)*Na⁽¹⁺⁾

1-(Phenanthridine-6'-formyl)-4-phenyl-3-thiosemicarbazone

Refernces

• 1、 -. "Method for selectively synthesizing dihydrophenanthridine or phenanthridine compound". Paragraph 0087-0090. . Retrieved 2021/07/01.
• 2、 Dong, Jianyang,Wang, Xiaochen,Song, Hongjian,Liu, Yuxiu,Wang, Qingmin. "Photoredox-Catalyzed Redox-Neutral Minisci C?H Formylation of N-Heteroarenes". . p. 2155 - 2159. Retrieved 2020/02/11.