N-(3-hydroxybutanoyl)homoserine lactone

Base Information

• Chemical Name: N-(3-hydroxybutanoyl)homoserine lactone
• CAS No.: 126049-72-7
• Molecular Formula: C₈H₁₃NO₄
• Molecular Weight: 187.196
• Mol file: 126049-72-7.mol

Synonyms:N-(3-Hydroxybutanoyl)homoserinelactone; N-(3-Hydroxybutyryl)-L-homoserine lactone; N-3-Hydroxybutanoyl-L-homoserinelactone; N-b-(3-Hydroxybutyryl)-L-homoserinelactone

Chemical Property of N-(3-hydroxybutanoyl)homoserine lactone

Chemical Property:

• Vapor Pressure: 2.69E-12mmHg at 25°C
• Boiling Point: 504.6°Cat760mmHg
• Flash Point: 259°C
• PSA: 79.12000
• Density: 1.25g/cm³
• LogP: 0.02930

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(3-hydroxybutanoyl)homoserine lactone

There total 2 articles about N-(3-hydroxybutanoyl)homoserine lactone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(R)-3-hydroxybutyric acid (625-72-9,26063-00-3,29435-48-1) + L-homoserine lactone (2185-02-6) → (R)-3-Hydroxy-N-((S)-2-oxo-tetrahydro-furan-3-yl)-butyramide (126049-72-7)

Guidance literature:

With benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide; In dichloromethane;

DOI:10.1016/0040-4039(96)00142-6

Reference yield:

→ C4-HSL (912545-51-8,1325550-06-8,126049-72-7)

Guidance literature:

upstream raw materials:

(R)-3-hydroxybutyric acid

L-homoserine lactone

Refernces

• 1、 Dekhane, Mouloud,Douglas, Kenneth T.,Gilbert, Peter. "A novel convenient route to the naturally occurring 3-oxoacyl-L-homoserinelactones and related bacterial autoinducers". . p. 1883 - 1884. Retrieved 2007/10/03.