Telomycin

Base Information

• Chemical Name: Telomycin
• CAS No.: 19246-24-3
• Molecular Formula: C59H77N13O19
• Molecular Weight: 1272.36
• European Community (EC) Number: 242-913-9
• NSC Number: 235069
• Mol file: 19246-24-3.mol

Synonyms:L-beta-aspartyl-L-seryl-L-threonyl-L-allothreonyl-L-alanylglycyl-trans-3-hydroxy-L-prolyl-eryth ro-3-hydroxy-L-leucyl-beta-methyl-L-tryptophyl-alpha,beta-didehydro-L-tryptophyl-cis-3-hydroxy-L-proline beta(1)-lactone;telomycin

Chemical Property of Telomycin

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.6700 (estimate)
• Boiling Point: 1760.9°Cat760mmHg
• Flash Point: 1018.7°C
• PSA: 495.77000
• Density: 1.5g/cm³
• LogP: -1.65350
• XLogP3: -3.7
• Hydrogen Bond Donor Count: 17
• Hydrogen Bond Acceptor Count: 20
• Rotatable Bond Count: 13
• Exact Mass: 1271.54586728
• Heavy Atom Count: 91
• Complexity: 2760

Purity/Quality:

99% ^*data from raw suppliers

Telomycin ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1C(C(=O)NC(C(=O)NC(C(=O)NCC(=O)N2CCC(C2C(=O)NC(=CC3=CNC4=CC=CC=C43)C(=O)NC(C(=O)NC(C(=O)N5CCC(C5C(=O)O1)O)C(C(C)C)O)C(C)C6=CNC7=CC=CC=C76)O)C)C(C)O)NC(=O)C(CO)NC(=O)CC(C(=O)O)N
• Isomeric SMILES: CC1C(C(=O)NC(C(=O)NC(C(=O)NCC(=O)N2CCC(C2C(=O)N/C(=C\C3=CNC4=CC=CC=C43)/C(=O)NC(C(=O)NC(C(=O)N5CCC(C5C(=O)O1)O)C(C(C)C)O)C(C)C6=CNC7=CC=CC=C76)O)C)C(C)O)NC(=O)C(CO)NC(=O)CC(C(=O)O)N
• Uses: Telomycin is a complex, high molecular weight depsipeptide discovered in 1958. The structure was subsequently solved in 1968. Telomycin possesses potent and highly selective activity against Gram positive bacteria in vitro and in vivo when given by intramuscular administration. Telomycin is poorly absorbed after oral administration. Despite its structural novelty, telomycin has received little attention. Telomycin is a complex, high molecular weight depsipeptide discovered in 1958. The structure was not solved until 1968. Telomycin possesses potent and highly selective activity against Gram positive bacteria in vitro and in vivo when given by intramuscular administration. Telomycin is poorly absorbed after oral administration. Despite its structural novelty, telomycin has received little attention. Telomycin is an antibiotic that potently inhibits gram-postive bacteria.

Technology Process of Telomycin

There total 1 articles about Telomycin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C67H91N13O20 → telomycin (19246-24-3)

Guidance literature:

With recombinant Tem₂₅; Enzymatic reaction;

DOI:10.1021/jacs.5b01794

Refernces