S-benzyl-N-(benzyloxycarbonyl)-L-cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-S-benzyl-L-cysteinyl-L-prolyl-L-leucylglycinamide

Base Information

• Chemical Name: S-benzyl-N-(benzyloxycarbonyl)-L-cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-S-benzyl-L-cysteinyl-L-prolyl-L-leucylglycinamide
• CAS No.: 3274-73-5
• Molecular Formula: C₆₅H₈₆N₁₂O₁₄S₂
• Molecular Weight: 1323.6
• Mol file: 3274-73-5.mol

Synonyms:Glycinamide,S-benzyl-N-carboxy-L-cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-S-benzyl-L-cysteinyl-L-prolyl-L-leucyl-,benzyl ester (6CI,7CI,8CI); Z-S-Benzyl-cysteine-tyrosine-isoleucine-glutamine-asparagine-S-benzyl-cysteine-proline-leucine-glycine-NH2

Chemical Property of S-benzyl-N-(benzyloxycarbonyl)-L-cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-S-benzyl-L-cysteinyl-L-prolyl-L-leucylglycinamide

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 1622.2°Cat760mmHg
• Flash Point: 934.9°C
• Density: 1.299g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of S-benzyl-N-(benzyloxycarbonyl)-L-cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-S-benzyl-L-cysteinyl-L-prolyl-L-leucylglycinamide

There total 6 articles about S-benzyl-N-(benzyloxycarbonyl)-L-cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-S-benzyl-L-cysteinyl-L-prolyl-L-leucylglycinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ S-benzyl-N-benzyloxycarbonyl-cysteinyl=>tyrosyl=>isoleucyl=>glutaminyl=>asparaginyl=>S-benzyl-cysteinyl=>prolyl=>leucyl=>-glycin-amide (1675-08-7,3274-73-5,3410-72-8,4587-31-9,6739-39-5,7165-55-1,7776-64-9,106765-66-6,106819-71-0,106819-72-1)

Guidance literature:

With ammonia; sodium; Erwaermen des Reaktionsprodukts mit Diaethylphosphonat und Tetraaethyl-diphosphit und anschliessend mit N-<S-Benzyl-N-benzyloxycarbonyl-L-cysteinyl>-L-tyrosin;

DOI:10.1021/ja01641a004

Reference yield:

→ S-benzyl-N-benzyloxycarbonyl-cysteinyl=>tyrosyl=>isoleucyl=>glutaminyl=>asparaginyl=>S-benzyl-cysteinyl=>prolyl=>leucyl=>-glycin-amide (1675-08-7,3274-73-5,3410-72-8,4587-31-9,6739-39-5,7165-55-1,7776-64-9,106765-66-6,106819-71-0,106819-72-1)

Guidance literature:

With hydrogen bromide; acetic acid; Behandeln des Reaktionsprodukts mit Triaethylamin und S-Benzyl-N-benzyloxycarbonyl-L-cystein-<4-nitro-phenylester> in DMF;

DOI:10.1021/ja01530a040

Reference yield:

→ S-benzyl-N-benzyloxycarbonyl-cysteinyl=>tyrosyl=>isoleucyl=>glutaminyl=>asparaginyl=>S-benzyl-cysteinyl=>prolyl=>leucyl=>-glycin-amide (1675-08-7,3274-73-5,3410-72-8,4587-31-9,6739-39-5,7165-55-1,7776-64-9,106765-66-6,106819-71-0,106819-72-1)

Guidance literature:

With triethylamine; N,N-dimethyl-formamide; isobutyl chloroformate; anschliessend Behandeln mit N-<N-<1-(S-Benzyl-L-cysteinyl)-L-prolyl>-L-leucyl>-glycin-amid-sesquihydrat unter Zusatz von Triaethylamin oder von 2-Chlor-benzo<1,3,2>dioxophospholan oder von Dicyclohexylcarbodiimid;

DOI:10.1021/ja01519a053

upstream raw materials:

N-(fluoren-9-ylmethoxycarbonyl)glycine

Downstream raw materials:

oxytocin

Refernces