5alpha-Pregnane-3,20-dione

Base Information Edit

Chemical Name:5alpha-Pregnane-3,20-dione
CAS No.:566-65-4
Molecular Formula:C21H32O2
Molecular Weight:316.484
Hs Code.:
European Community (EC) Number:209-297-3
NSC Number:18319
UNII:98G4S1OH0Z
DSSTox Substance ID:DTXSID301017277
Nikkaji Number:J6.519F
Wikipedia:5%CE%B1-Dihydroprogesterone
Wikidata:Q4641508
Metabolomics Workbench ID:35449
ChEMBL ID:CHEMBL407717
Mol file:566-65-4.mol

Synonyms:3,20 Allopregnanedione;3,20-Allopregnanedione;3,20-Allopregnanedione, (5alpha)-Isomer;3,20-Allopregnanedione, (5beta,13alpha,17alpha)-Isomer;5 alpha Dihydroprogesterone;5 alpha Pregnane 3,20 dione;5 alpha Pregnanedione;5 alpha-Dihydroprogesterone;5 alpha-Pregnane-3,20-dione;5 beta Dihydroprogesterone;5 beta Pregnane 3,20 dione;5 beta-Pregnane-3,20-dione;5-alpha-Dihydroprogesterone;5-alpha-Pregnane-3,20-dione;5-alpha-Pregnanedione;5-beta-Dihydroprogesterone;5alpha DHP;5alpha Pregnane 3,20 dione;5alpha-DHP;5alpha-Pregnane-3,20-dione;5beta DHP;5beta-DHP

Suppliers and Price of 5alpha-Pregnane-3,20-dione

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(5α)-Pregnane-3,20-dione
10g
$ 305.00

TRC
(5α)-Pregnane-3,20-dione
1g
$ 120.00

TRC
(5α)-Pregnane-3,20-dione
500mg
$ 70.00

TCI Chemical
5α-Pregnane-3,20-dione
1G
$ 53.00

TCI Chemical
5α-Pregnane-3,20-dione
5G
$ 263.00

Sigma-Aldrich
5α-Pregnane-3,20-dione (allo) progesterone metabolite
1g
$ 253.00

Sigma-Aldrich
5α-Pregnane-3,20-dione (allo) progesterone metabolite
500mg
$ 141.00

Medical Isotopes, Inc.
5α-Pregnan-3,20-dione-1,2,4,5,6,7-d6
5 mg
$ 495.00

Matrix Scientific
Pregnane-3,20-dione
5g
$ 380.00

Matrix Scientific
Pregnane-3,20-dione
1g
$ 120.00

Total 92 raw suppliers

Chemical Property of 5alpha-Pregnane-3,20-dione Edit

Chemical Property:

Appearance/Colour:White solid
Vapor Pressure:1.43E-07mmHg at 25°C
Melting Point:200 °C
Refractive Index:1.515
Boiling Point:429.2 °C at 760 mmHg
Flash Point:160.3 °C
PSA：34.14000
Density:1.048 g/cm³
LogP:4.80340
Storage Temp.:Sealed in dry,Room Temperature
Solubility.:Chloroform (Slightly), Ethyl Acetate (Slightly)
XLogP3:4.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:316.240230259
Heavy Atom Count:23
Complexity:538

Purity/Quality:

97% ^*data from raw suppliers

(5α)-Pregnane-3,20-dione ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CC(=O)C1CCC2C1(CCC3C2CCC4C3(CCC(=O)C4)C)C
Isomeric SMILES:CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(CCC(=O)C4)C)C
Description 5α-Dihydroprogesterone?(5α-DHP) is an?endogenous?progestogen?and?neurosteroid?that is?synthesized?from?progesterone.It is also an?intermediate?in the synthesis of?allopregnanolone?and?isopregnanolone?from progesterone.
Uses (5α)-Pregnane-3,20-dione exerts neuroprotective effects in chronic autoimmune encephalomyelitis (EAE). The neuroactivity of the steroid acts as a therapeutic agent for multiple sclerosis.

Technology Process of 5alpha-Pregnane-3,20-dione

There total 66 articles about 5alpha-Pregnane-3,20-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%