1-[N-[N-(2-Aminobenzoyl)glycyl]-4-nitro-L-phenylalanyl]-L-proline

Base Information

• Chemical Name: 1-[N-[N-(2-Aminobenzoyl)glycyl]-4-nitro-L-phenylalanyl]-L-proline
• CAS No.: 67482-93-3
• Molecular Formula: C23H25N5O7
• Molecular Weight: 483.481
• European Community (EC) Number: 266-699-1
• DSSTox Substance ID: DTXSID30986863
• Nikkaji Number: J310.254H
• Mol file: 67482-93-3.mol

Synonyms:2-ABZ-Gly-4-NO2-Phe-Pro;2-aminobenzoylglycyl-4-nitrophenylalanyl-proline;4-nitrophenylalanyl-prolyl-2-aminohippuric acid;o-aminobenzoylglycyl-p-nitro-L-phenylalanyl-L-proline

Chemical Property of 1-[N-[N-(2-Aminobenzoyl)glycyl]-4-nitro-L-phenylalanyl]-L-proline

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.648
• Boiling Point: 908.1 °C at 760 mmHg
• Flash Point: 503 °C
• PSA: 187.65000
• Density: 1.427 g/cm³
• LogP: 2.53400
• Storage Temp.: -15°C
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 8
• Exact Mass: 483.17539815
• Heavy Atom Count: 35
• Complexity: 809

Purity/Quality:

99% ^*data from raw suppliers

o-Aminobenzoylglycyl-p-nitro-L-phenylalanyl-L-proline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC(N(C1)C(=O)C(CC2=CC=C(C=C2)[N+](=O)[O-])NC(=O)CNC(=O)C3=CC=CC=C3N)C(=O)O
• Isomeric SMILES: C1C[C@H](N(C1)C(=O)[C@H](CC2=CC=C(C=C2)[N+](=O)[O-])NC(=O)CNC(=O)C3=CC=CC=C3N)C(=O)O
• Uses: o-Aminobenzoylglycyl-p-nitro-L-phenylalanyl-L-proline (cas# 67482-93-3) is substrate for the fluorescent assay of angiotensin I-?converting enzyme and of the bacterial dipeptidyl carboxypeptidase from Escherichia coli.

Technology Process of 1-[N-[N-(2-Aminobenzoyl)glycyl]-4-nitro-L-phenylalanyl]-L-proline

There total 1 articles about 1-[N-[N-(2-Aminobenzoyl)glycyl]-4-nitro-L-phenylalanyl]-L-proline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(2-aminobenzoyl)-glycine (526-21-6) + (S)-1-[(S)-2-Amino-3-(4-nitro-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid → o-aminobenzoylglycyl-p-nitro-L-phenylalanyl-L-proline (67482-93-3)

Guidance literature:

With angiotensin I converting enzyme; In water; dimethyl sulfoxide; Equilibrium constant; buffer (pH 8);

DOI:10.1248/cpb.37.145

Reference yield:

o-aminobenzoylglycyl-p-nitro-L-phenylalanyl-L-proline (67482-93-3) → N-(2-aminobenzoyl)-glycine (526-21-6) + (S)-1-[(S)-2-Amino-3-(4-nitro-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid

Guidance literature:

With angiotensin I converting enzyme; In water; dimethyl sulfoxide; Rate constant; Equilibrium constant; buffer (pH 8);

DOI:10.1248/cpb.37.145

upstream raw materials:

N-(2-aminobenzoyl)-glycine

Downstream raw materials:

N-(2-aminobenzoyl)-glycine

Refernces