benzimidazol-2-one

Base Information

• Chemical Name: benzimidazol-2-one
• CAS No.: 43135-91-7
• Molecular Formula: C7H4 N2 O
• Molecular Weight: 132.122
• Hs Code.: 2933990090
• Mol file: 43135-91-7.mol

Synonyms:Benzimidazolone

Chemical Property of benzimidazol-2-one

Chemical Property:

• Vapor Pressure: 0.0232mmHg at 25°C
• Refractive Index: 1.701
• Boiling Point: 249.3 °C at 760 mmHg
• Flash Point: 98.6 °C
• PSA: 41.79000
• Density: 1.39g/cm³
• LogP: -1.06940

Purity/Quality:

99% ^*data from raw suppliers

2H-Benzo[d]imidazol-2-one 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of benzimidazol-2-one

There total 12 articles about benzimidazol-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

→ 1,3-benzimidazol-2-one (43135-91-7)

Guidance literature:

Reference yield: 98.0%

1,2-diamino-benzene (95-54-5) + 1,1'-carbonyldiimidazole (530-62-1) → 1,3-benzimidazol-2-one (43135-91-7)

Guidance literature:

With polyethylene glycol 300; In tetrahydrofuran; at 160 ℃; for 16h;

DOI:10.3390/molecules24132447

Reference yield: 98.0%

1,3-diacetyl-1,3-dihydro-benzoimidazol-2-one (2735-73-1) → 1,3-benzimidazol-2-one (43135-91-7)

Guidance literature:

In dichloromethane;

upstream raw materials:

benzo[1,2,5]thiadiazole

bis(trichloromethyl) carbonate

p-aminoethylbenzoate

1,3-diacetyl-1,3-dihydro-benzoimidazol-2-one

Downstream raw materials:

1,3-bis(hydroxymethyl)benzimidazolin-2-one

1,3-bis(2-hydroxyethyl)-1H-benzo[d]imidazol-2(3H)-one

Refernces

• 1、 -. "Method for preparing carbonyl heterocyclic compound". Paragraph 0054-0059; 0078-0083. . Retrieved 2020/03/25.
• 2、 Hao, Leiduan,Zhao, Yanfei,Yu, Bo,Zhang, Hongye,Xu, Huanjun,Liu, Zhimin. "Au catalyzed synthesis of benzimidazoles from 2-nitroanilines and CO 2/H2". . p. 3039 - 3044. Retrieved 2014/06/10.