Ambazone

Base Information

• Chemical Name: Ambazone
• CAS No.: 539-21-9
• Molecular Formula: C8H11 N7 S
• Molecular Weight: 237.288
• Hs Code.: 2930909090
• European Community (EC) Number: 208-713-0
• UNII: BYK4592A3Q
• DSSTox Substance ID: DTXSID3046407
• Nikkaji Number: J9.411K
• Wikipedia: Ambazone
• Wikidata: Q414317
• NCI Thesaurus Code: C72627
• ChEMBL ID: CHEMBL2103762,CHEMBL1414870,CHEMBL3198213
• Mol file: 539-21-9.mol

Synonyms:1,4-benzoquinone guanylhydrazone thiosemicarbazone;1,4-benzoquinone guanylhydrazone thiosemicarbazone monohydrochloride;ambazone

Chemical Property of Ambazone

Chemical Property:

• Vapor Pressure: 1.03E-08mmHg at 25°C
• Melting Point: 195°C (rough estimate)
• Refractive Index: 1.5500 (estimate)
• Boiling Point: 461.9°Cat760mmHg
• Flash Point: 233.2°C
• PSA: 156.76000
• Density: 1.57g/cm³
• LogP: 1.42280
• Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
• Solubility.: DMSO (Slightly), Methanol (Slightly)
• XLogP3: 0.7
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 237.07966455
• Heavy Atom Count: 16
• Complexity: 289

Purity/Quality:

99%, ^*data from raw suppliers

Ambazone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC(=CC=C1NN=C(N)N)N=NC(=S)N
• Uses: Ambazone is a benzoquidine diimine derivative useful as animal growth substance.
• Therapeutic Function: Antiseptic

Technology Process of Ambazone

There total 3 articles about Ambazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dihydroambazone (61566-17-4) → ambazone (539-21-9)

Guidance literature:

With oxygen; In water; various pH-values; inhibition through ascorbic acid;

Reference yield:

[1,4]benzoquinone mono-carbamimidoylhydrazone (7316-92-9) + thiosemicarbazide (79-19-6) → ambazone (539-21-9)

Guidance literature:

Reference yield:

→ ambazone (539-21-9)

Guidance literature:

Benzochinon-(1,4)-monoguanylhydrazon, 1. wss. ethanol. HCl, Thiosemicarbazid, 2. wss. NH3;

upstream raw materials:

[1,4]benzoquinone mono-carbamimidoylhydrazone

thiosemicarbazide

dihydroambazone

Refernces

• 1、 Miosga,Schulze,Hesse,Romer. "Chemical-analytical characterization of dihydroambazone". . p. 541 - 543. Retrieved 2007/10/02.