Technology Process of 12-Methylbenz(a)acridine
There total 10 articles about 12-Methylbenz(a)acridine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
naphthalene-2-boronic acid; 2-aminoacetophenone;
With
copper diacetate;
In
2,2,2-trifluoroethanol;
at 20 ℃;
for 12h;
With
t-butyl bromide;
In
2,2,2-trifluoroethanol;
at 20 ℃;
for 24h;
DOI:10.1021/acs.joc.0c00137
- Guidance literature:
-
N-Phenyl-2-naphthylamine; acetic acid;
With
zinc(II) chloride;
at 180 ℃;
Inert atmosphere;
With
sodium hydroxide;
at 250 ℃;
for 5h;
Inert atmosphere;
DOI:10.1039/c3ob42600a
- Guidance literature:
-
Multi-step reaction with 2 steps
1: potassium carbonate; copper-powder; nitrobenzene
With
copper; potassium carbonate; nitrobenzene;
DOI:10.1021/ja01264a052