6-Ethyl-2-piperidinone

Base Information

• Chemical Name: 6-Ethyl-2-piperidinone
• CAS No.: 53611-44-2
• Molecular Formula: C₇H₁₃NO
• Molecular Weight: 127.186
• Hs Code.: 2933790090
• Mol file: 53611-44-2.mol

Synonyms:6-Aethyl-piperidin-2-on;Purine,6-(ethylthio)-7-methyl;6-Aethylmercapto-7-methyl-7H-purin;6-ethylpiperidin-2-one;6-Ethylmercapto-7-methylpurine;6-ethylmercapto-7-methyl-7H-purine;Purine,6-(ethylthio)-7-methyl-(8CI);7H-Purine,6-(ethylthio)-7-methyl;

Chemical Property of 6-Ethyl-2-piperidinone

Chemical Property:

• Vapor Pressure: 0.009mmHg at 25°C
• Refractive Index: 1.438
• Boiling Point: 266.531 °C at 760 mmHg
• Flash Point: 148.864 °C
• PSA: 29.10000
• Density: 0.931 g/cm³
• LogP: 1.39390
• Storage Temp.: 2-8°C

Purity/Quality:

98%Min ^*data from raw suppliers

6-ethylpiperidin-2-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-Ethyl-2-piperidinone

There total 8 articles about 6-Ethyl-2-piperidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

N-(phenylthio)hept-5-enamide → hept-5-enamide + 7-Methylcaprolactam (1985-48-4,17377-76-3,538369-20-9) + 6-ethyl-piperidin-2-one (53611-44-2)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In benzene; for 4h; Heating;

DOI:10.1021/ol060983q

Reference yield: 65.0%

piperidine-2,6-dione (1121-89-7) + ethylmagnesium bromide (925-90-6) → 6-ethyl-piperidin-2-one (53611-44-2)

Guidance literature:

piperidine-2,6-dione; ethylmagnesium bromide; In diethyl ether; at -78 - 20 ℃;

With hydrogenchloride; sodium cyanoborohydride; In diethyl ether; pH=3 - 4;

Reference yield: 19.1%

2-ethylpiperidine (1484-80-6,78738-37-1) → 6-ethyl-piperidin-2-one (53611-44-2)

Guidance literature:

With CrMCM-41; dihydrogen peroxide; In methanol; for 20h; Heating;

upstream raw materials:

sulfuric acid

2-Ethylcyclopentanone oxime

2-ethylpiperidine

2-ethylcyclopentanone

Refernces

• 1、 -. "THIOPHENE DERIVATIVE". Page/Page column 29. . Retrieved 2012/03/26.
• 2、 -. "NOVEL QUINOXALINE DERIVATIVES". Page/Page column 196-197. . Retrieved 2008/06/13.