3-Bromo-6-quinolineacetic acid

Base Information

• Chemical Name: 3-Bromo-6-quinolineacetic acid
• CAS No.: 1022091-93-5
• Molecular Formula: C11H8BrNO2
• Molecular Weight: 266.09
• Hs Code.: 2933499090
• Mol file: 1022091-93-5.mol

Synonyms:2-(3-Bromoquinolin-6-Yl)Acetic Acid

Chemical Property of 3-Bromo-6-quinolineacetic acid

Chemical Property:

• Boiling Point: 419.9±30.0 °C(Predicted)
• PKA: 3.95±0.30(Predicted)
• PSA: 50.19000
• Density: 1.658
• LogP: 2.62440
• Storage Temp.: 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

2-(3-Bromoquinolin-6-yl)aceticAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Bromo-6-quinolineacetic acid

There total 1 articles about 3-Bromo-6-quinolineacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.5%

methyl 2-(3-bromoquinolin-6-yl)acetate (1022091-89-9) → (3-bromo-quinolin-6-yl)-acetic acid (1022091-93-5)

Guidance literature:

methyl 2-(3-bromoquinolin-6-yl)acetate; With sodium hydroxide; water; for 1.5h; Heating / reflux;

With hydrogenchloride; In water; pH=4;

Reference yield:

methanol (67-56-1) + (3-bromo-quinolin-6-yl)-acetic acid (1022091-93-5) → methyl 2-(3-bromoquinolin-6-yl)acetate (1022091-89-9)

Guidance literature:

methanol; (3-bromo-quinolin-6-yl)-acetic acid; With sulfuric acid; for 18h; Heating / reflux;

With sodium sulfate; Product distribution / selectivity;

upstream raw materials:

methyl 2-(3-bromoquinolin-6-yl)acetate

Downstream raw materials:

methyl 2-(3-bromoquinolin-6-yl)acetate

Refernces