4-Benzyloxyphenylethyl octanoate

Base Information

• Chemical Name: 4-Benzyloxyphenylethyl octanoate
• CAS No.: 137422-37-8
• Molecular Formula: C24H32O3
• Molecular Weight: 368.516
• Mol file: 137422-37-8.mol

Synonyms:4-Benzyloxyphenylethyl octanoate;Nonanoic acid 2-[4-(phenylMethoxy)-phenyl]-ethyl ester

Chemical Property of 4-Benzyloxyphenylethyl octanoate

Chemical Property:

• Boiling Point: 485.2±25.0 °C(Predicted)
• PSA: 35.53000
• Density: 1.026±0.06 g/cm3(Predicted)
• LogP: 6.10190

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Benzyloxyphenylethyl octanoate

There total 4 articles about 4-Benzyloxyphenylethyl octanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-[4-(benzyloxy)benzyl]acetic acid (6547-53-1) → β-(4-Benzyloxy)phenylethyl nonanoate (137422-37-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 92.7 percent / BH₃ / tetrahydrofuran

2: Et₃N

With borane; triethylamine; In tetrahydrofuran;

Reference yield:

(4-benzyloxy-phenyl)-acetic acid methyl ester (68641-16-7) → β-(4-Benzyloxy)phenylethyl nonanoate (137422-37-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 90.3 percent / LAH / diethyl ether / 21 h / Heating

2: Et₃N

With lithium aluminium tetrahydride; triethylamine; In diethyl ether;

Reference yield:

2-(4-(benzyloxy)phenyl)acetyl chloride (39188-62-0) → β-(4-Benzyloxy)phenylethyl nonanoate (137422-37-8)

Guidance literature:

Multi-step reaction with 3 steps

1: Et₃N / CH₂Cl₂ / 1) room temp., 17 h, 2) reflux, 1 h

2: 90.3 percent / LAH / diethyl ether / 21 h / Heating

3: Et₃N

With lithium aluminium tetrahydride; triethylamine; In diethyl ether; dichloromethane;

upstream raw materials:

Nonanoyl chloride

2-(4-benzyloxyphenyl)ethanol

2-(4-(benzyloxy)phenyl)acetyl chloride

2-[4-(benzyloxy)benzyl]acetic acid

Downstream raw materials:

4-Dodecyloxy-benzoic acid 4-(2-nonanoyloxy-ethyl)-phenyl ester

4-Decyloxy-benzoic acid 4-(2-nonanoyloxy-ethyl)-phenyl ester

4-Octyloxy-benzoic acid 4-(2-nonanoyloxy-ethyl)-phenyl ester

4-Hexyloxy-benzoic acid 4-(2-nonanoyloxy-ethyl)-phenyl ester

Refernces