N-(5-bromopyridin-3-yl)benzenesulfonamide

Base Information

• Chemical Name: N-(5-bromopyridin-3-yl)benzenesulfonamide
• CAS No.: 1084-12-4
• Molecular Formula: C11H9BrN2O2S
• Molecular Weight: 313.175
• Hs Code.: 2935009090
• Mol file: 1084-12-4.mol

Synonyms:N-(5-bromopyridin-3-yl)benzenesulfonamide;N-(5-BroMo-3-pyridyl)benzenesulfonaMide, 96%

Chemical Property of N-(5-bromopyridin-3-yl)benzenesulfonamide

Chemical Property:

• PSA: 67.44000
• LogP: 3.79870
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

N-(5-Bromopyridin-3-yl)benzenesulfonamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(5-bromopyridin-3-yl)benzenesulfonamide

There total 5 articles about N-(5-bromopyridin-3-yl)benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3-amino-5-bromopyridine (13535-01-8) + benzenesulfonyl chloride (98-09-9) → N-(5-bromopyridin-3-yl)benzenesulfonamide (1084-12-4)

Guidance literature:

With pyridine; at 20 ℃; for 16h;

Reference yield: 99.0%

N-(5-bromopyridin-3-yl)-N-(phenylsulfonyl)benzenesulfonamide (1192749-74-8) → N-(5-bromopyridin-3-yl)benzenesulfonamide (1084-12-4)

Guidance literature:

With methanol; sodium hydroxide; water; at 20 ℃; for 3h; Product distribution / selectivity;

Reference yield: 84.0%

→ N-(5-bromopyridin-3-yl)benzenesulfonamide (1084-12-4)

Guidance literature:

With pyridine; In dichloromethane; at 0 - 20 ℃;

upstream raw materials:

3-amino-5-bromopyridine

benzenesulfonyl chloride

N-(5-bromopyridin-3-yl)-N-(phenylsulfonyl)benzenesulfonamide

Downstream raw materials:

N-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)-benzenesulfonamide

N-[5-(8-chloro-1,5-naphthyridin-2-yl)-3-pyridinyl]benzenesulfonamide

N-{5-[8-(4-pyridinyl)-1,5-naphthyridin-2-yl]-3-pyridinyl}benzenesulfonamide

N-{5-[8-(4-morpholinyl)-1,5-naphthyridin-2-yl]-3-pyridinyl}benzenesulfonamide

Refernces

• 1、 -. "PHOSPHOTIDYLINOSITOL 3-KINASE INHIBITORS". Page/Page column 38. . Retrieved 2017/12/05.
• 2、 -. "INDAZOLE INHIBITORS OF THE WNT SIGNAL PATHWAY AND THERAPEUTIC USES THEREOF". Paragraph 0420-0421; 0437. . Retrieved 2013/10/22.