Sophoramine

Base Information

• Chemical Name: Sophoramine
• CAS No.: 6882-66-2
• Molecular Formula: C₁₅H₂₀N₂O
• Molecular Weight: 244.337
• DSSTox Substance ID: DTXSID00218926
• Nikkaji Number: J15.613B
• Wikidata: Q27108306
• Metabolomics Workbench ID: 68308
• ChEMBL ID: CHEMBL3590540
• Mol file: 6882-66-2.mol

Synonyms:sophoramine

Chemical Property of Sophoramine

Chemical Property:

• Vapor Pressure: 1.73E-08mmHg at 25°C
• Refractive Index: 1.628
• Boiling Point: 455.6 °C at 760 mmHg
• Flash Point: 216.3 °C
• PSA: 25.24000
• Density: 1.22 g/cm³
• LogP: 1.75780
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 244.157563266
• Heavy Atom Count: 18
• Complexity: 440

Purity/Quality:

99% ^*data from raw suppliers

Sophoramine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC2CN3C(=O)C=CC=C3C4C2N(C1)CCC4
• Isomeric SMILES: C1C[C@H]2CN3C(=O)C=CC=C3[C@@H]4[C@H]2N(C1)CCC4
• Description: An alkaloid present in Sophora alopecuroides, the base possesses the tetracyclic structure characteristic of the Sophora alkaloids. It is 1aevorotatory with [α]D - 90.85° or - 98° (EtOH). It yields a series of well crystalline salts and derivatives including the hydrochloride, m.p. 247-8° (dec.); hydriodide, m.p. 294-6°C; aurichloride, m.p. 183-4°C (dec.); p1atinich1oride, m.p. 245-7°C (dec.); picrate, m.p. 229-231°C (dec.) and the picrolonate, m.p. 173-5°C (dec.).
• Uses: Sophoramine is a quinolizidine alkaloid isolated from traditional Chinese herbal drugssuch as Sophora flavescens Ait. (Kushen), S. alopecuroides L. (Kudouzi or Kugancao) and S. tonkinensis Gapnep (Shandougen).

Technology Process of Sophoramine

There total 1 articles about Sophoramine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ Sophoramin (6838-34-2,6882-66-2,51095-74-0,52932-74-8)

Guidance literature:

aus Darvasolin, P2O5;

DOI:10.1007/BF00568271