methyl oxetane-3-carboxylate

Base Information

• Chemical Name: methyl oxetane-3-carboxylate
• CAS No.: 1638760-80-1
• Molecular Formula: C₅H₈O₃
• Molecular Weight: 116.117
• Mol file: 1638760-80-1.mol

Synonyms:

Chemical Property of methyl oxetane-3-carboxylate

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl oxetane-3-carboxylate

There total 3 articles about methyl oxetane-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.5%

C12H16O6S → 3-oxetanecarboxylic acid methyl ester (1638760-80-1)

Guidance literature:

With potassium tert-butylate; In tert-butyl alcohol; at 60 - 70 ℃; Large scale;

Reference yield:

methanol (67-56-1) + (1RS,2RS)-1-(oxetan-3-yl)-2-phenylethane-1,2-diol + C11H14O3 → 3-oxetanecarboxylic acid methyl ester (1638760-80-1)

Guidance literature:

methanol; (1RS,2RS)-1-(oxetan-3-yl)-2-phenylethane-1,2-diol; C₁₁H₁₄O₃; With sodium periodate; In water; at 0 - 20 ℃; for 3h; Inert atmosphere;

With bromine; sodium hydrogencarbonate; In methanol; water; at 0 - 20 ℃; for 3h; Inert atmosphere;

DOI:10.1016/j.tet.2016.03.078

Reference yield:

methanol (67-56-1) + (1RS,2RS)-1-(oxetan-3-yl)-2-phenylethane-1,2-diol → 3-oxetanecarboxylic acid methyl ester (1638760-80-1)

Guidance literature:

methanol; (1RS,2RS)-1-(oxetan-3-yl)-2-phenylethane-1,2-diol; With sodium periodate; In water; at 20 ℃; Inert atmosphere;

With bromine; sodium hydrogencarbonate; In water; at 0 ℃; Inert atmosphere;

DOI:10.1016/j.tet.2016.03.078

upstream raw materials:

methanol

Downstream raw materials:

oxetane-3-carboxylic acid

Refernces

• 1、 -. "Synthesis method of 3-oxyheterocyclic butane carboxylic acid". Paragraph 0048; 0051; 0052. . Retrieved 2018/11/22.