Potassium5-Formyl-2-thiophenetrifluoroborate

Base Information

• Chemical Name: Potassium5-Formyl-2-thiophenetrifluoroborate
• CAS No.: 1025113-78-3
• Molecular Formula: C5H3BF3KOS
• Molecular Weight: 218.049
• Mol file: 1025113-78-3.mol

Synonyms:Potassium 5-formylthiophene-2-trifluoroborate;trifluoro(5-forMyl-thiophen-2-yl)-Borate potassiuM salt;Potassium trifluoro(5-formylthien-2-yl)borate

Chemical Property of Potassium5-Formyl-2-thiophenetrifluoroborate

Chemical Property:

• PSA: 45.31000
• LogP: 1.61500

Purity/Quality:

98.5% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Potassium5-Formyl-2-thiophenetrifluoroborate

There total 2 articles about Potassium5-Formyl-2-thiophenetrifluoroborate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

(5-formylthiophen-2-yl)boronic acid → potassium (5-formylthiophen-2-yl)trifluoroborate (1025113-78-3)

Guidance literature:

With potassium hydrogenfluoride; In methanol; water; at 0 ℃; Inert atmosphere;

DOI:10.1021/ol901395c

Reference yield: 72.0%

potassium hydrogen difluoride + (5-formylthiophen-2-yl)boronic acid → potassium (5-formylthiophen-2-yl)trifluoroborate (1025113-78-3)

Guidance literature:

With water; In methanol; at 0 - 20 ℃; for 0.5h; Inert atmosphere;

DOI:10.1002/ejoc.201300529

Reference yield: 94.0%

potassium (5-formylthiophen-2-yl)trifluoroborate (1025113-78-3) + [(p-methylphenyl)sulfonylmethyl]isonitrile (38622-91-2,36635-61-7) → potassium 5-(2-trifluoroboratothiophen-5-yl)-4-(toluene-4-sulfonyl)-4,5-dihydrooxazole

Guidance literature:

With polystyrene-bound 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetonitrile; at 20 ℃; for 12h;

DOI:10.1021/ol901395c

Downstream raw materials:

potassium 5-((cyclohexylamino)methyl)thiophen-2-yltrifluoroborate

4-(5-(5-methyl-1H-benzo[d]imidazol-2-yl)thiophen-2-yl)benzonitrile

Refernces

• 1、 -. "MOLECULAR ROTOR-BASED D-AMINO ACIDS AS TOOLS FOR IMAGING PEPTIDOGLYCAN BIOSYNTHESIS". Paragraph 0134-0136. . Retrieved 2019/08/29.
• 2、 Molander, Gary A.,Febo-Ayala, Wilma,Jean-Gerard, Ludivine. "Condensation reactions to form oxazoline-substituted potassium organotrifluoroborates". supporting information; experimental part. p. 3830 - 3833. Retrieved 2009/12/05.