Technology Process of Methyl (Z)-6-methylhept-4-enoate
There total 4 articles about Methyl (Z)-6-methylhept-4-enoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: pyridinium chlorochromate (PCC), sodium acetate / CH2Cl2 / 1.5 h / Ambient temperature
2: 1.) t-BuOK / 1.) DMF, RT, 5 min, 2.) a) RT, 20 h, b) 90 deg C, 1 h
With
potassium tert-butylate; sodium acetate; pyridinium chlorochromate;
In
dichloromethane;
DOI:10.1021/jo00240a024
- Guidance literature:
-
(3-(methoxycarbonyl)propyl)triphenylphosphonium bromide;
With
sodium hexamethyldisilazane;
In
tetrahydrofuran;
at -20 ℃;
for 0.333333h;
Inert atmosphere;
isobutyraldehyde;
In
tetrahydrofuran;
at -78 - 20 ℃;
Inert atmosphere;
DOI:10.1039/c2cc31148h
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: acetonitrile / 6 h / Reflux; Inert atmosphere
2.1: sodium hexamethyldisilazane / tetrahydrofuran / 0.33 h / -20 °C / Inert atmosphere
2.2: -78 - 20 °C / Inert atmosphere
With
sodium hexamethyldisilazane;
In
tetrahydrofuran; acetonitrile;
DOI:10.1039/c2cc31148h
